LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T WZ3105
0.04
uM
LJP5
 72
hr
 765 483 3124 0.1546 -0.1195
Hs 578T XMD11-50
0.04
uM
LJP6
 72
hr
 765 3057 3124 0.9784 0.9714
Hs 578T Y39983
0.04
uM
LJP6
 72
hr
 765 2784 3124 0.8912 0.8560
Hs 578T YM 201636
0.04
uM
LJP5
 72
hr
 765 3131 3124 1.0022 1.0029
Hs 578T ZSTK474
0.04
uM
LJP6
 72
hr
 765 2489 3124 0.7967 0.7308
Hs 578T Afatinib
0.12
uM
LJP6
 72
hr
 765 2876 3124 0.9206 0.8948
Hs 578T Sigma A6730
0.12
uM
LJP5
 72
hr
 765 3018 3124 0.9660 0.9550
Hs 578T Alvocidib
0.12
uM
LJP6
 72
hr
 765 434 3124 0.1391 -0.1400
Hs 578T AT-7519
0.12
uM
LJP6
 72
hr
 765 2279 3124 0.7296 0.6419
Hs 578T AZD 5438
0.12
uM
LJP6
 72
hr
 765 2334 3124 0.7471 0.6651
Hs 578T AZD-6482
0.12
uM
LJP5
 72
hr
 765 2738 3124 0.8764 0.8363
Hs 578T AZD7762
0.12
uM
LJP6
 72
hr
 765 632 3124 0.2025 -0.0561
Hs 578T AZD8055
0.12
uM
LJP6
 72
hr
 765 1030 3124 0.3299 0.1126
Hs 578T AZD8330
0.12
uM
LJP5
 72
hr
 765 1054 3124 0.3375 0.1228
Hs 578T Barasertib
0.12
uM
LJP5
 72
hr
 765 1128 3124 0.3611 0.1540
Hs 578T BI-2536
0.12
uM
LJP6
 72
hr
 765 400 3124 0.1280 -0.1547
Hs 578T BMS345541
0.12
uM
LJP6
 72
hr
 765 3036 3124 0.9717 0.9625
Hs 578T SNS-032
0.12
uM
LJP6
 72
hr
 765 419 3124 0.1341 -0.1467
Hs 578T GDC-0980
0.12
uM
LJP5
 72
hr
 765 1475 3124 0.4722 0.3010
Hs 578T NVP-AEW541
0.12
uM
LJP5
 72
hr
 765 3194 3124 1.0222 1.0294
Hs 578T SB590885
0.12
uM
LJP5
 72
hr
 765 3734 3124 1.1953 1.2586
Hs 578T PIK-93
0.12
uM
LJP5
 72
hr
 765 3184 3124 1.0191 1.0253
Hs 578T KIN001-043
0.12
uM
LJP6
 72
hr
 765 3135 3124 1.0036 1.0047
Hs 578T Alpelisib
0.12
uM
LJP5
 72
hr
 765 2884 3124 0.9232 0.8983
Hs 578T Luminespib
0.12
uM
LJP5
 72
hr
 765 676 3124 0.2164 -0.0377