LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T TGX221
3.33
uM
LJP5
 72
hr
 765 1568 3124 0.5018 0.3403
Hs 578T Torin1
3.33
uM
LJP6
 72
hr
 765 698 3124 0.2236 -0.0281
Hs 578T Torin2
3.33
uM
LJP5
 72
hr
 765 495 3124 0.1585 -0.1143
Hs 578T Tozasertib
3.33
uM
LJP5
 72
hr
 765 770 3124 0.2465 0.0022
Hs 578T Trametinib
3.33
uM
LJP5
 72
hr
 765 1001 3124 0.3206 0.1003
Hs 578T TWS119
3.33
uM
LJP5
 72
hr
 765 2298 3124 0.7356 0.6498
Hs 578T Vemurafenib
3.33
uM
LJP5
 72
hr
 765 3014 3124 0.9647 0.9533
Hs 578T Withaferin A
3.33
uM
LJP5
 72
hr
 765 605 3124 0.1936 -0.0678
Hs 578T Withaferin A
3.33
uM
LJP6
 72
hr
 765 593 3124 0.1899 -0.0728
Hs 578T WYE-125132
3.33
uM
LJP6
 72
hr
 765 875 3124 0.2803 0.0469
Hs 578T WZ3105
3.33
uM
LJP5
 72
hr
 765 412 3124 0.1319 -0.1496
Hs 578T XMD11-50
3.33
uM
LJP6
 72
hr
 765 1520 3124 0.4867 0.3203
Hs 578T Y39983
3.33
uM
LJP6
 72
hr
 765 2018 3124 0.6459 0.5310
Hs 578T YM 201636
3.33
uM
LJP5
 72
hr
 765 2090 3124 0.6689 0.5615
Hs 578T ZSTK474
3.33
uM
LJP6
 72
hr
 765 1087 3124 0.3480 0.1366
Hs 578T Afatinib
10.0
uM
LJP6
 72
hr
 765 491 3124 0.1571 -0.1162
Hs 578T Sigma A6730
10.0
uM
LJP5
 72
hr
 765 1264 3124 0.4047 0.2116
Hs 578T Alvocidib
10.0
uM
LJP6
 72
hr
 765 374 3124 0.1197 -0.1657
Hs 578T AT-7519
10.0
uM
LJP6
 72
hr
 765 266 3124 0.0852 -0.2114
Hs 578T AZD 5438
10.0
uM
LJP6
 72
hr
 765 401 3124 0.1285 -0.1542
Hs 578T AZD-6482
10.0
uM
LJP5
 72
hr
 765 1071 3124 0.3429 0.1298
Hs 578T AZD7762
10.0
uM
LJP6
 72
hr
 765 315 3124 0.1008 -0.1907
Hs 578T AZD8055
10.0
uM
LJP6
 72
hr
 765 510 3124 0.1634 -0.1078
Hs 578T AZD8330
10.0
uM
LJP5
 72
hr
 765 916 3124 0.2934 0.0643
Hs 578T Barasertib
10.0
uM
LJP5
 72
hr
 765 863 3124 0.2763 0.0417