LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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MCF 10A | AZD-6482 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 10786 | 11155 | 0.9669 | 0.9609 |
MCF 10A | AZD7762 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 7703 | 11155 | 0.6905 | 0.6351 |
MCF 10A | AZD8055 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 4177 | 11155 | 0.3744 | 0.2624 |
MCF 10A | AZD8330 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 2427 | 11155 | 0.2176 | 0.0775 |
MCF 10A | Barasertib | 0.12 | uM | LJP5 | 72 | hr | 1694 | 1920 | 11155 | 0.1721 | 0.0239 |
MCF 10A | BI-2536 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 1063 | 11155 | 0.0953 | -0.0666 |
MCF 10A | BMS345541 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 10725 | 11155 | 0.9615 | 0.9546 |
MCF 10A | SNS-032 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 1915 | 11155 | 0.1717 | 0.0234 |
MCF 10A | GDC-0980 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 7230 | 11155 | 0.6481 | 0.5851 |
MCF 10A | NVP-AEW541 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 10777 | 11155 | 0.9661 | 0.9600 |
MCF 10A | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 11072 | 11155 | 0.9925 | 0.9912 |
MCF 10A | PIK-93 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 11269 | 11155 | 1.0102 | 1.0120 |
MCF 10A | KIN001-043 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 11044 | 11155 | 0.9900 | 0.9882 |
MCF 10A | Alpelisib | 0.12 | uM | LJP5 | 72 | hr | 1694 | 9995 | 11155 | 0.8960 | 0.8773 |
MCF 10A | Luminespib | 0.12 | uM | LJP5 | 72 | hr | 1694 | 1256 | 11155 | 0.1126 | -0.0463 |
MCF 10A | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 7992 | 11155 | 0.7165 | 0.6657 |
MCF 10A | OSI-027 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 8354 | 11155 | 0.7489 | 0.7039 |
MCF 10A | XMD11-85h | 0.12 | uM | LJP6 | 72 | hr | 1694 | 11124 | 11155 | 0.9972 | 0.9967 |
MCF 10A | HG-6-64-01 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 11177 | 11155 | 1.0019 | 1.0023 |
MCF 10A | WH-4-025 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 10071 | 11155 | 0.9028 | 0.8854 |
MCF 10A | WZ-4-145 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 10407 | 11155 | 0.9329 | 0.9209 |
MCF 10A | XMD16-144 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 6112 | 11155 | 0.5479 | 0.4670 |
MCF 10A | Brivanib | 0.12 | uM | LJP5 | 72 | hr | 1694 | 10774 | 11155 | 0.9658 | 0.9597 |
MCF 10A | Buparlisib | 0.12 | uM | LJP5 | 72 | hr | 1694 | 10775 | 11155 | 0.9659 | 0.9598 |
MCF 10A | BX-912 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 10402 | 11155 | 0.9325 | 0.9204 |