LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A AZD-6482
0.12
uM
LJP5
72
hr
1694 10786 11155 0.9669 0.9609
MCF 10A AZD7762
0.12
uM
LJP6
72
hr
1694 7703 11155 0.6905 0.6351
MCF 10A AZD8055
0.12
uM
LJP6
72
hr
1694 4177 11155 0.3744 0.2624
MCF 10A AZD8330
0.12
uM
LJP5
72
hr
1694 2427 11155 0.2176 0.0775
MCF 10A Barasertib
0.12
uM
LJP5
72
hr
1694 1920 11155 0.1721 0.0239
MCF 10A BI-2536
0.12
uM
LJP6
72
hr
1694 1063 11155 0.0953 -0.0666
MCF 10A BMS345541
0.12
uM
LJP6
72
hr
1694 10725 11155 0.9615 0.9546
MCF 10A SNS-032
0.12
uM
LJP6
72
hr
1694 1915 11155 0.1717 0.0234
MCF 10A GDC-0980
0.12
uM
LJP5
72
hr
1694 7230 11155 0.6481 0.5851
MCF 10A NVP-AEW541
0.12
uM
LJP5
72
hr
1694 10777 11155 0.9661 0.9600
MCF 10A SB590885
0.12
uM
LJP5
72
hr
1694 11072 11155 0.9925 0.9912
MCF 10A PIK-93
0.12
uM
LJP5
72
hr
1694 11269 11155 1.0102 1.0120
MCF 10A KIN001-043
0.12
uM
LJP6
72
hr
1694 11044 11155 0.9900 0.9882
MCF 10A Alpelisib
0.12
uM
LJP5
72
hr
1694 9995 11155 0.8960 0.8773
MCF 10A Luminespib
0.12
uM
LJP5
72
hr
1694 1256 11155 0.1126 -0.0463
MCF 10A A443654
0.12
uM
LJP6
72
hr
1694 7992 11155 0.7165 0.6657
MCF 10A OSI-027
0.12
uM
LJP6
72
hr
1694 8354 11155 0.7489 0.7039
MCF 10A XMD11-85h
0.12
uM
LJP6
72
hr
1694 11124 11155 0.9972 0.9967
MCF 10A HG-6-64-01
0.12
uM
LJP6
72
hr
1694 11177 11155 1.0019 1.0023
MCF 10A WH-4-025
0.12
uM
LJP5
72
hr
1694 10071 11155 0.9028 0.8854
MCF 10A WZ-4-145
0.12
uM
LJP6
72
hr
1694 10407 11155 0.9329 0.9209
MCF 10A XMD16-144
0.12
uM
LJP5
72
hr
1694 6112 11155 0.5479 0.4670
MCF 10A Brivanib
0.12
uM
LJP5
72
hr
1694 10774 11155 0.9658 0.9597
MCF 10A Buparlisib
0.12
uM
LJP5
72
hr
1694 10775 11155 0.9659 0.9598
MCF 10A BX-912
0.12
uM
LJP5
72
hr
1694 10402 11155 0.9325 0.9204