LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Selumetinib
0.04
uM
LJP6
 72
hr
 1694 6318 11155 0.5664 0.4887
MCF 10A Sirolimus
0.04
uM
LJP6
 72
hr
 1694 12244 11155 1.0976 1.1151
MCF 10A Sorafenib
0.04
uM
LJP6
 72
hr
 1694 12063 11155 1.0814 1.0959
MCF 10A SU11274
0.04
uM
LJP5
 72
hr
 1694 11406 11155 1.0225 1.0265
MCF 10A Fedratinib
0.04
uM
LJP5
 72
hr
 1694 11139 11155 0.9985 0.9983
MCF 10A TGX221
0.04
uM
LJP5
 72
hr
 1694 10749 11155 0.9636 0.9571
MCF 10A Torin1
0.04
uM
LJP6
 72
hr
 1694 6130 11155 0.5496 0.4689
MCF 10A Torin2
0.04
uM
LJP5
 72
hr
 1694 4382 11155 0.3929 0.2841
MCF 10A Tozasertib
0.04
uM
LJP5
 72
hr
 1694 6349 11155 0.5692 0.4920
MCF 10A Trametinib
0.04
uM
LJP5
 72
hr
 1694 2756 11155 0.2471 0.1122
MCF 10A TWS119
0.04
uM
LJP5
 72
hr
 1694 11487 11155 1.0298 1.0351
MCF 10A Vemurafenib
0.04
uM
LJP5
 72
hr
 1694 10963 11155 0.9828 0.9797
MCF 10A Withaferin A
0.04
uM
LJP5
 72
hr
 1694 11065 11155 0.9919 0.9905
MCF 10A Withaferin A
0.04
uM
LJP6
 72
hr
 1694 11354 11155 1.0178 1.0210
MCF 10A WYE-125132
0.04
uM
LJP6
 72
hr
 1694 6905 11155 0.6190 0.5507
MCF 10A WZ3105
0.04
uM
LJP5
 72
hr
 1694 5838 11155 0.5234 0.4380
MCF 10A XMD11-50
0.04
uM
LJP6
 72
hr
 1694 11028 11155 0.9886 0.9865
MCF 10A Y39983
0.04
uM
LJP6
 72
hr
 1694 10738 11155 0.9626 0.9559
MCF 10A YM 201636
0.04
uM
LJP5
 72
hr
 1694 11383 11155 1.0204 1.0240
MCF 10A ZSTK474
0.04
uM
LJP6
 72
hr
 1694 10958 11155 0.9823 0.9792
MCF 10A Afatinib
0.12
uM
LJP6
 72
hr
 1694 1655 11155 0.1484 -0.0041
MCF 10A Sigma A6730
0.12
uM
LJP5
 72
hr
 1694 10798 11155 0.9679 0.9622
MCF 10A Alvocidib
0.12
uM
LJP6
 72
hr
 1694 610 11155 0.0547 -0.1145
MCF 10A AT-7519
0.12
uM
LJP6
 72
hr
 1694 10552 11155 0.9459 0.9362
MCF 10A AZD 5438
0.12
uM
LJP6
 72
hr
 1694 9687 11155 0.8684 0.8448