LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Nintedanib
0.04
uM
LJP6
 72
hr
 1694 11315 11155 1.0143 1.0169
MCF 10A NU7441
0.04
uM
LJP5
 72
hr
 1694 11501 11155 1.0310 1.0366
MCF 10A Dactolisib
0.04
uM
LJP5
 72
hr
 1694 6617 11155 0.5932 0.5204
MCF 10A NVP-TAE684
0.04
uM
LJP6
 72
hr
 1694 9965 11155 0.8933 0.8742
MCF 10A Palbociclib
0.04
uM
LJP6
 72
hr
 1694 9116 11155 0.8172 0.7844
MCF 10A PD0325901
0.04
uM
LJP5
 72
hr
 1694 3665 11155 0.3286 0.2083
MCF 10A PD0325901
0.04
uM
LJP6
 72
hr
 1694 3467 11155 0.3108 0.1874
MCF 10A PD173074
0.04
uM
LJP6
 72
hr
 1694 11608 11155 1.0406 1.0478
MCF 10A PD184352
0.04
uM
LJP5
 72
hr
 1694 6894 11155 0.6180 0.5496
MCF 10A Pelitinib
0.04
uM
LJP5
 72
hr
 1694 8699 11155 0.7798 0.7404
MCF 10A PF431396
0.04
uM
LJP5
 72
hr
 1694 7335 11155 0.6576 0.5963
MCF 10A PF477736
0.04
uM
LJP5
 72
hr
 1694 10659 11155 0.9555 0.9476
MCF 10A PF562271
0.04
uM
LJP6
 72
hr
 1694 9484 11155 0.8502 0.8233
MCF 10A PHA-665752
0.04
uM
LJP5
 72
hr
 1694 11057 11155 0.9912 0.9896
MCF 10A PHA-793887
0.04
uM
LJP6
 72
hr
 1694 3799 11155 0.3406 0.2225
MCF 10A PI103
0.04
uM
LJP6
 72
hr
 1694 11606 11155 1.0404 1.0476
MCF 10A PLX-4720
0.04
uM
LJP5
 72
hr
 1694 11201 11155 1.0041 1.0048
MCF 10A QL-X-138
0.04
uM
LJP6
 72
hr
 1694 12300 11155 1.1026 1.1210
MCF 10A QL-XII-47
0.04
uM
LJP6
 72
hr
 1694 11090 11155 0.9942 0.9931
MCF 10A Radicicol
0.04
uM
LJP5
 72
hr
 1694 9940 11155 0.8911 0.8716
MCF 10A Radicicol
0.04
uM
LJP6
 72
hr
 1694 9703 11155 0.8698 0.8465
MCF 10A Seliciclib
0.04
uM
LJP5
 72
hr
 1694 11082 11155 0.9935 0.9923
MCF 10A Ruxolitinib
0.04
uM
LJP5
 72
hr
 1694 10858 11155 0.9733 0.9685
MCF 10A XL147
0.04
uM
LJP5
 72
hr
 1694 11313 11155 1.0141 1.0167
MCF 10A Saracatinib
0.04
uM
LJP6
 72
hr
 1694 11431 11155 1.0247 1.0291