LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A R406
0.04
uM
LJP6
 72
hr
 1694 11540 11155 1.0345 1.0407
MCF 10A Pictilisib
0.04
uM
LJP6
 72
hr
 1694 9923 11155 0.8896 0.8698
MCF 10A Gefitinib
0.04
uM
LJP6
 72
hr
 1694 10005 11155 0.8969 0.8785
MCF 10A Geldanamycin
0.04
uM
LJP5
 72
hr
 1694 2692 11155 0.2413 0.1055
MCF 10A Geldanamycin
0.04
uM
LJP6
 72
hr
 1694 2367 11155 0.2122 0.0712
MCF 10A GSK1059615
0.04
uM
LJP5
 72
hr
 1694 11327 11155 1.0154 1.0181
MCF 10A GSK1059615
0.04
uM
LJP6
 72
hr
 1694 11024 11155 0.9883 0.9862
MCF 10A GSK1904529A
0.04
uM
LJP6
 72
hr
 1694 7707 11155 0.6909 0.6355
MCF 10A Omipalisib
0.04
uM
LJP6
 72
hr
 1694 2233 11155 0.2002 0.0569
MCF 10A GSK 690693
0.04
uM
LJP5
 72
hr
 1694 11282 11155 1.0113 1.0134
MCF 10A GW843682X
0.04
uM
LJP6
 72
hr
 1694 11015 11155 0.9874 0.9852
MCF 10A HG-5-113-01
0.04
uM
LJP5
 72
hr
 1694 10424 11155 0.9344 0.9227
MCF 10A HG-5-88-01
0.04
uM
LJP6
 72
hr
 1694 10451 11155 0.9369 0.9256
MCF 10A Imatinib
0.04
uM
LJP6
 72
hr
 1694 11138 11155 0.9984 0.9981
MCF 10A JNK-9L
0.04
uM
LJP6
 72
hr
 1694 11450 11155 1.0264 1.0311
MCF 10A JW-7-24-1
0.04
uM
LJP6
 72
hr
 1694 11170 11155 1.0013 1.0016
MCF 10A Lapatinib
0.04
uM
LJP6
 72
hr
 1694 10844 11155 0.9721 0.9671
MCF 10A LDN-193189
0.04
uM
LJP5
 72
hr
 1694 11145 11155 0.9991 0.9989
MCF 10A Linifanib
0.04
uM
LJP6
 72
hr
 1694 11701 11155 1.0489 1.0576
MCF 10A Linsitinib
0.04
uM
LJP5
 72
hr
 1694 10398 11155 0.9321 0.9200
MCF 10A Mitoxantrone
0.04
uM
LJP5
 72
hr
 1694 3239 11155 0.2904 0.1633
MCF 10A Mitoxantrone
0.04
uM
LJP6
 72
hr
 1694 3196 11155 0.2866 0.1588
MCF 10A MK2206
0.04
uM
LJP6
 72
hr
 1694 11562 11155 1.0364 1.0429
MCF 10A Neratinib
0.04
uM
LJP5
 72
hr
 1694 5640 11155 0.5056 0.4170
MCF 10A Nilotinib
0.04
uM
LJP5
 72
hr
 1694 11366 11155 1.0189 1.0222