LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Mitoxantrone
0.37
uM
LJP5
 72
hr
 1694 1623 11155 0.1456 -0.0075
MCF 10A Mitoxantrone
0.37
uM
LJP6
 72
hr
 1694 1479 11155 0.1326 -0.0228
MCF 10A MK2206
0.37
uM
LJP6
 72
hr
 1694 7386 11155 0.6621 0.6017
MCF 10A Neratinib
0.37
uM
LJP5
 72
hr
 1694 3558 11155 0.3189 0.1970
MCF 10A Nilotinib
0.37
uM
LJP5
 72
hr
 1694 11157 11155 1.0002 1.0002
MCF 10A Nintedanib
0.37
uM
LJP6
 72
hr
 1694 10967 11155 0.9831 0.9801
MCF 10A NU7441
0.37
uM
LJP5
 72
hr
 1694 10832 11155 0.9710 0.9658
MCF 10A Dactolisib
0.37
uM
LJP5
 72
hr
 1694 2879 11155 0.2581 0.1252
MCF 10A NVP-TAE684
0.37
uM
LJP6
 72
hr
 1694 6930 11155 0.6213 0.5535
MCF 10A Palbociclib
0.37
uM
LJP6
 72
hr
 1694 7285 11155 0.6530 0.5909
MCF 10A PD0325901
0.37
uM
LJP5
 72
hr
 1694 3235 11155 0.2901 0.1629
MCF 10A PD0325901
0.37
uM
LJP6
 72
hr
 1694 2960 11155 0.2654 0.1338
MCF 10A PD173074
0.37
uM
LJP6
 72
hr
 1694 11132 11155 0.9979 0.9976
MCF 10A PD184352
0.37
uM
LJP5
 72
hr
 1694 4821 11155 0.4322 0.3305
MCF 10A Pelitinib
0.37
uM
LJP5
 72
hr
 1694 2549 11155 0.2285 0.0903
MCF 10A PF431396
0.37
uM
LJP5
 72
hr
 1694 3664 11155 0.3284 0.2082
MCF 10A PF477736
0.37
uM
LJP5
 72
hr
 1694 8873 11155 0.7954 0.7587
MCF 10A PF562271
0.37
uM
LJP6
 72
hr
 1694 6920 11155 0.6203 0.5524
MCF 10A PHA-665752
0.37
uM
LJP5
 72
hr
 1694 10794 11155 0.9676 0.9618
MCF 10A PHA-793887
0.37
uM
LJP6
 72
hr
 1694 2711 11155 0.2430 0.1075
MCF 10A PI103
0.37
uM
LJP6
 72
hr
 1694 7232 11155 0.6483 0.5853
MCF 10A PLX-4720
0.37
uM
LJP5
 72
hr
 1694 10909 11155 0.9780 0.9740
MCF 10A QL-X-138
0.37
uM
LJP6
 72
hr
 1694 11489 11155 1.0299 1.0352
MCF 10A QL-XII-47
0.37
uM
LJP6
 72
hr
 1694 10729 11155 0.9618 0.9549
MCF 10A Radicicol
0.37
uM
LJP5
 72
hr
 1694 4503 11155 0.4037 0.2969