LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | PI103 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 2550 | 11155 | 0.2286 | 0.0904 |
MCF 10A | PLX-4720 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 12034 | 11155 | 1.0788 | 1.0929 |
MCF 10A | QL-X-138 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 8955 | 11155 | 0.8027 | 0.7674 |
MCF 10A | QL-XII-47 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 7834 | 11155 | 0.7022 | 0.6489 |
MCF 10A | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 1694 | 1519 | 11155 | 0.1362 | -0.0185 |
MCF 10A | Radicicol | 3.33 | uM | LJP6 | 72 | hr | 1694 | 1471 | 11155 | 0.1319 | -0.0235 |
MCF 10A | Seliciclib | 3.33 | uM | LJP5 | 72 | hr | 1694 | 10432 | 11155 | 0.9352 | 0.9236 |
MCF 10A | Ruxolitinib | 3.33 | uM | LJP5 | 72 | hr | 1694 | 10614 | 11155 | 0.9514 | 0.9428 |
MCF 10A | XL147 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 9760 | 11155 | 0.8749 | 0.8525 |
MCF 10A | Saracatinib | 3.33 | uM | LJP6 | 72 | hr | 1694 | 5938 | 11155 | 0.5323 | 0.4485 |
MCF 10A | Selumetinib | 3.33 | uM | LJP6 | 72 | hr | 1694 | 3276 | 11155 | 0.2937 | 0.1672 |
MCF 10A | Sirolimus | 3.33 | uM | LJP6 | 72 | hr | 1694 | 12704 | 11155 | 1.1388 | 1.1636 |
MCF 10A | Sorafenib | 3.33 | uM | LJP6 | 72 | hr | 1694 | 10506 | 11155 | 0.9418 | 0.9313 |
MCF 10A | SU11274 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 7486 | 11155 | 0.6711 | 0.6122 |
MCF 10A | Fedratinib | 3.33 | uM | LJP5 | 72 | hr | 1694 | 7024 | 11155 | 0.6296 | 0.5633 |
MCF 10A | TGX221 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 5070 | 11155 | 0.4545 | 0.3568 |
MCF 10A | Torin1 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 2554 | 11155 | 0.2290 | 0.0909 |
MCF 10A | Torin2 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 2174 | 11155 | 0.1949 | 0.0508 |
MCF 10A | Tozasertib | 3.33 | uM | LJP5 | 72 | hr | 1694 | 1961 | 11155 | 0.1758 | 0.0282 |
MCF 10A | Trametinib | 3.33 | uM | LJP5 | 72 | hr | 1694 | 3133 | 11155 | 0.2808 | 0.1521 |
MCF 10A | TWS119 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 10972 | 11155 | 0.9836 | 0.9807 |
MCF 10A | Vemurafenib | 3.33 | uM | LJP5 | 72 | hr | 1694 | 9108 | 11155 | 0.8165 | 0.7836 |
MCF 10A | Withaferin A | 3.33 | uM | LJP5 | 72 | hr | 1694 | 480 | 11155 | 0.0430 | -0.1283 |
MCF 10A | Withaferin A | 3.33 | uM | LJP6 | 72 | hr | 1694 | 405 | 11155 | 0.0363 | -0.1362 |
MCF 10A | WYE-125132 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 2780 | 11155 | 0.2492 | 0.1148 |