LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A PI103
3.33
uM
LJP6
72
hr
1694 2550 11155 0.2286 0.0904
MCF 10A PLX-4720
3.33
uM
LJP5
72
hr
1694 12034 11155 1.0788 1.0929
MCF 10A QL-X-138
3.33
uM
LJP6
72
hr
1694 8955 11155 0.8027 0.7674
MCF 10A QL-XII-47
3.33
uM
LJP6
72
hr
1694 7834 11155 0.7022 0.6489
MCF 10A Radicicol
3.33
uM
LJP5
72
hr
1694 1519 11155 0.1362 -0.0185
MCF 10A Radicicol
3.33
uM
LJP6
72
hr
1694 1471 11155 0.1319 -0.0235
MCF 10A Seliciclib
3.33
uM
LJP5
72
hr
1694 10432 11155 0.9352 0.9236
MCF 10A Ruxolitinib
3.33
uM
LJP5
72
hr
1694 10614 11155 0.9514 0.9428
MCF 10A XL147
3.33
uM
LJP5
72
hr
1694 9760 11155 0.8749 0.8525
MCF 10A Saracatinib
3.33
uM
LJP6
72
hr
1694 5938 11155 0.5323 0.4485
MCF 10A Selumetinib
3.33
uM
LJP6
72
hr
1694 3276 11155 0.2937 0.1672
MCF 10A Sirolimus
3.33
uM
LJP6
72
hr
1694 12704 11155 1.1388 1.1636
MCF 10A Sorafenib
3.33
uM
LJP6
72
hr
1694 10506 11155 0.9418 0.9313
MCF 10A SU11274
3.33
uM
LJP5
72
hr
1694 7486 11155 0.6711 0.6122
MCF 10A Fedratinib
3.33
uM
LJP5
72
hr
1694 7024 11155 0.6296 0.5633
MCF 10A TGX221
3.33
uM
LJP5
72
hr
1694 5070 11155 0.4545 0.3568
MCF 10A Torin1
3.33
uM
LJP6
72
hr
1694 2554 11155 0.2290 0.0909
MCF 10A Torin2
3.33
uM
LJP5
72
hr
1694 2174 11155 0.1949 0.0508
MCF 10A Tozasertib
3.33
uM
LJP5
72
hr
1694 1961 11155 0.1758 0.0282
MCF 10A Trametinib
3.33
uM
LJP5
72
hr
1694 3133 11155 0.2808 0.1521
MCF 10A TWS119
3.33
uM
LJP5
72
hr
1694 10972 11155 0.9836 0.9807
MCF 10A Vemurafenib
3.33
uM
LJP5
72
hr
1694 9108 11155 0.8165 0.7836
MCF 10A Withaferin A
3.33
uM
LJP5
72
hr
1694 480 11155 0.0430 -0.1283
MCF 10A Withaferin A
3.33
uM
LJP6
72
hr
1694 405 11155 0.0363 -0.1362
MCF 10A WYE-125132
3.33
uM
LJP6
72
hr
1694 2780 11155 0.2492 0.1148