LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Radicicol
0.37
uM
LJP6
 72
hr
 1694 4177 11155 0.3745 0.2624
MCF 10A Seliciclib
0.37
uM
LJP5
 72
hr
 1694 10578 11155 0.9483 0.9390
MCF 10A Ruxolitinib
0.37
uM
LJP5
 72
hr
 1694 10910 11155 0.9780 0.9741
MCF 10A XL147
0.37
uM
LJP5
 72
hr
 1694 10465 11155 0.9381 0.9270
MCF 10A Saracatinib
0.37
uM
LJP6
 72
hr
 1694 10020 11155 0.8982 0.8800
MCF 10A Selumetinib
0.37
uM
LJP6
 72
hr
 1694 3915 11155 0.3510 0.2348
MCF 10A Sirolimus
0.37
uM
LJP6
 72
hr
 1694 12534 11155 1.1236 1.1457
MCF 10A Sorafenib
0.37
uM
LJP6
 72
hr
 1694 11440 11155 1.0255 1.0301
MCF 10A SU11274
0.37
uM
LJP5
 72
hr
 1694 10329 11155 0.9259 0.9126
MCF 10A Fedratinib
0.37
uM
LJP5
 72
hr
 1694 10354 11155 0.9282 0.9153
MCF 10A TGX221
0.37
uM
LJP5
 72
hr
 1694 10872 11155 0.9746 0.9701
MCF 10A Torin1
0.37
uM
LJP6
 72
hr
 1694 2899 11155 0.2599 0.1274
MCF 10A Torin2
0.37
uM
LJP5
 72
hr
 1694 2038 11155 0.1827 0.0364
MCF 10A Tozasertib
0.37
uM
LJP5
 72
hr
 1694 2067 11155 0.1854 0.0395
MCF 10A Trametinib
0.37
uM
LJP5
 72
hr
 1694 3044 11155 0.2729 0.1427
MCF 10A TWS119
0.37
uM
LJP5
 72
hr
 1694 11511 11155 1.0319 1.0376
MCF 10A Vemurafenib
0.37
uM
LJP5
 72
hr
 1694 10972 11155 0.9836 0.9807
MCF 10A Withaferin A
0.37
uM
LJP5
 72
hr
 1694 9899 11155 0.8874 0.8672
MCF 10A Withaferin A
0.37
uM
LJP6
 72
hr
 1694 9848 11155 0.8828 0.8618
MCF 10A WYE-125132
0.37
uM
LJP6
 72
hr
 1694 3270 11155 0.2931 0.1665
MCF 10A WZ3105
0.37
uM
LJP5
 72
hr
 1694 916 11155 0.0821 -0.0823
MCF 10A XMD11-50
0.37
uM
LJP6
 72
hr
 1694 9518 11155 0.8533 0.8270
MCF 10A Y39983
0.37
uM
LJP6
 72
hr
 1694 9405 11155 0.8431 0.8150
MCF 10A YM 201636
0.37
uM
LJP5
 72
hr
 1694 10243 11155 0.9183 0.9036
MCF 10A ZSTK474
0.37
uM
LJP6
 72
hr
 1694 8257 11155 0.7402 0.6937