LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Afatinib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 1789 | 11155 | 0.1604 | 0.0100 |
| MCF 10A | Sigma A6730 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 10506 | 11155 | 0.9418 | 0.9313 |
| MCF 10A | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 299 | 11155 | 0.0269 | -0.1474 |
| MCF 10A | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 623 | 11155 | 0.0559 | -0.1132 |
| MCF 10A | AZD 5438 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 1677 | 11155 | 0.1504 | -0.0018 |
| MCF 10A | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 9840 | 11155 | 0.8821 | 0.8610 |
| MCF 10A | AZD7762 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 5059 | 11155 | 0.4535 | 0.3557 |
| MCF 10A | AZD8055 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 2755 | 11155 | 0.2470 | 0.1122 |
| MCF 10A | AZD8330 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2628 | 11155 | 0.2356 | 0.0987 |
| MCF 10A | Barasertib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 1993 | 11155 | 0.1787 | 0.0316 |
| MCF 10A | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 1247 | 11155 | 0.1118 | -0.0472 |
| MCF 10A | BMS345541 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 10400 | 11155 | 0.9323 | 0.9202 |
| MCF 10A | SNS-032 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 309 | 11155 | 0.0278 | -0.1463 |
| MCF 10A | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2526 | 11155 | 0.2265 | 0.0879 |
| MCF 10A | NVP-AEW541 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 8455 | 11155 | 0.7579 | 0.7146 |
| MCF 10A | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 11212 | 11155 | 1.0051 | 1.0060 |
| MCF 10A | PIK-93 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 10884 | 11155 | 0.9757 | 0.9713 |
| MCF 10A | KIN001-043 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 10833 | 11155 | 0.9711 | 0.9660 |
| MCF 10A | Alpelisib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 9390 | 11155 | 0.8418 | 0.8135 |
| MCF 10A | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 1306 | 11155 | 0.1171 | -0.0410 |
| MCF 10A | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 2348 | 11155 | 0.2105 | 0.0692 |
| MCF 10A | OSI-027 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 4119 | 11155 | 0.3692 | 0.2563 |
| MCF 10A | XMD11-85h | 1.11 | uM | LJP6 | 72 | hr | 1694 | 10893 | 11155 | 0.9765 | 0.9723 |
| MCF 10A | HG-6-64-01 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 10460 | 11155 | 0.9377 | 0.9265 |
| MCF 10A | WH-4-025 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 5793 | 11155 | 0.5193 | 0.4332 |