LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 8941 | 11155 | 0.8015 | 0.7660 |
| MCF 10A | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2092 | 11155 | 0.1876 | 0.0421 |
| MCF 10A | Brivanib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 9380 | 11155 | 0.8409 | 0.8124 |
| MCF 10A | Buparlisib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 5137 | 11155 | 0.4605 | 0.3639 |
| MCF 10A | BX-912 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2557 | 11155 | 0.2293 | 0.0913 |
| MCF 10A | Canertinib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 2738 | 11155 | 0.2455 | 0.1104 |
| MCF 10A | Celastrol | 1.11 | uM | LJP6 | 72 | hr | 1694 | 6759 | 11155 | 0.6059 | 0.5354 |
| MCF 10A | CGP60474 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 408 | 11155 | 0.0366 | -0.1360 |
| MCF 10A | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 364 | 11155 | 0.0327 | -0.1406 |
| MCF 10A | CHIR-99021 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 11631 | 11155 | 1.0427 | 1.0503 |
| MCF 10A | CP724714 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 10697 | 11155 | 0.9589 | 0.9515 |
| MCF 10A | CP466722 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 11205 | 11155 | 1.0045 | 1.0053 |
| MCF 10A | Crizotinib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 9823 | 11155 | 0.8805 | 0.8592 |
| MCF 10A | Momelotinib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 8936 | 11155 | 0.8011 | 0.7654 |
| MCF 10A | Dasatinib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2422 | 11155 | 0.2171 | 0.0770 |
| MCF 10A | Dasatinib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 2061 | 11155 | 0.1848 | 0.0388 |
| MCF 10A | Dovitinib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 5375 | 11155 | 0.4819 | 0.3891 |
| MCF 10A | Enzastaurin | 1.11 | uM | LJP5 | 72 | hr | 1694 | 11564 | 11155 | 1.0366 | 1.0432 |
| MCF 10A | Erlotinib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2452 | 11155 | 0.2199 | 0.0802 |
| MCF 10A | Foretinib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 5525 | 11155 | 0.4953 | 0.4049 |
| MCF 10A | R406 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 10766 | 11155 | 0.9651 | 0.9589 |
| MCF 10A | Pictilisib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 5141 | 11155 | 0.4609 | 0.3644 |
| MCF 10A | Gefitinib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 2260 | 11155 | 0.2026 | 0.0598 |
| MCF 10A | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 1694 | 1452 | 11155 | 0.1302 | -0.0256 |
| MCF 10A | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 1694 | 1213 | 11155 | 0.1087 | -0.0509 |