LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | R406 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 8673 | 11155 | 0.7775 | 0.7377 |
| MCF 10A | Pictilisib | 10.0 | uM | LJP6 | 72 | hr | 1694 | 2457 | 11155 | 0.2203 | 0.0807 |
| MCF 10A | Gefitinib | 10.0 | uM | LJP6 | 72 | hr | 1694 | 2309 | 11155 | 0.2070 | 0.0650 |
| MCF 10A | Geldanamycin | 10.0 | uM | LJP5 | 72 | hr | 1694 | 925 | 11155 | 0.0829 | -0.0813 |
| MCF 10A | Geldanamycin | 10.0 | uM | LJP6 | 72 | hr | 1694 | 819 | 11155 | 0.0734 | -0.0925 |
| MCF 10A | GSK1059615 | 10.0 | uM | LJP5 | 72 | hr | 1694 | 1469 | 11155 | 0.1317 | -0.0238 |
| MCF 10A | GSK1059615 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 1500 | 11155 | 0.1345 | -0.0205 |
| MCF 10A | GSK1904529A | 10.0 | uM | LJP6 | 72 | hr | 1694 | 6329 | 11155 | 0.5674 | 0.4899 |
| MCF 10A | Omipalisib | 10.0 | uM | LJP6 | 72 | hr | 1694 | 925 | 11155 | 0.0829 | -0.0813 |
| MCF 10A | GSK 690693 | 10.0 | uM | LJP5 | 72 | hr | 1694 | 10102 | 11155 | 0.9056 | 0.8886 |
| MCF 10A | GW843682X | 10.0 | uM | LJP6 | 72 | hr | 1694 | 715 | 11155 | 0.0641 | -0.1035 |
| MCF 10A | HG-5-113-01 | 10.0 | uM | LJP5 | 72 | hr | 1694 | 1256 | 11155 | 0.1127 | -0.0463 |
| MCF 10A | HG-5-88-01 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 5518 | 11155 | 0.4947 | 0.4042 |
| MCF 10A | Imatinib | 10.0 | uM | LJP6 | 72 | hr | 1694 | 11340 | 11155 | 1.0166 | 1.0196 |
| MCF 10A | JNK-9L | 10.0 | uM | LJP6 | 72 | hr | 1694 | 1045 | 11155 | 0.0937 | -0.0686 |
| MCF 10A | JW-7-24-1 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 3936 | 11155 | 0.3529 | 0.2370 |
| MCF 10A | Lapatinib | 10.0 | uM | LJP6 | 72 | hr | 1694 | 4508 | 11155 | 0.4041 | 0.2974 |
| MCF 10A | LDN-193189 | 10.0 | uM | LJP5 | 72 | hr | 1694 | 294 | 11155 | 0.0264 | -0.1480 |
| MCF 10A | Linifanib | 10.0 | uM | LJP6 | 72 | hr | 1694 | 9388 | 11155 | 0.8416 | 0.8132 |
| MCF 10A | Linsitinib | 10.0 | uM | LJP5 | 72 | hr | 1694 | 6268 | 11155 | 0.5619 | 0.4835 |
| MCF 10A | Mitoxantrone | 10.0 | uM | LJP5 | 72 | hr | 1694 | 992 | 11155 | 0.0889 | -0.0742 |
| MCF 10A | Mitoxantrone | 10.0 | uM | LJP6 | 72 | hr | 1694 | 697 | 11155 | 0.0625 | -0.1054 |
| MCF 10A | MK2206 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 5446 | 11155 | 0.4882 | 0.3966 |
| MCF 10A | Neratinib | 10.0 | uM | LJP5 | 72 | hr | 1694 | 2463 | 11155 | 0.2208 | 0.0813 |
| MCF 10A | Nilotinib | 10.0 | uM | LJP5 | 72 | hr | 1694 | 5985 | 11155 | 0.5365 | 0.4535 |