LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Mitoxantrone | 0.12 | uM | LJP5 | 72 | hr | 1389 | 1605 | 5667 | 0.2832 | 0.0505 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 72 | hr | 1389 | 1375 | 5667 | 0.2427 | -0.0031 |
| MCF7 | MK2206 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 3511 | 5667 | 0.6195 | 0.4960 |
| MCF7 | Neratinib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 3990 | 5667 | 0.7041 | 0.6080 |
| MCF7 | Nilotinib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 6333 | 5667 | 1.1174 | 1.1556 |
| MCF7 | Nintedanib | 0.12 | uM | LJP6 | 72 | hr | 1389 | 4739 | 5667 | 0.8361 | 0.7829 |
| MCF7 | NU7441 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5677 | 5667 | 1.0016 | 1.0021 |
| MCF7 | Dactolisib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 2050 | 5667 | 0.3618 | 0.1546 |
| MCF7 | NVP-TAE684 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 2262 | 5667 | 0.3992 | 0.2041 |
| MCF7 | Palbociclib | 0.12 | uM | LJP6 | 72 | hr | 1389 | 3951 | 5667 | 0.6972 | 0.5989 |
| MCF7 | PD0325901 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 3513 | 5667 | 0.6199 | 0.4965 |
| MCF7 | PD0325901 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 3310 | 5667 | 0.5841 | 0.4490 |
| MCF7 | PD173074 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 5836 | 5667 | 1.0297 | 1.0394 |
| MCF7 | PD184352 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5122 | 5667 | 0.9037 | 0.8724 |
| MCF7 | Pelitinib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5611 | 5667 | 0.9900 | 0.9867 |
| MCF7 | PF431396 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 3602 | 5667 | 0.6355 | 0.5172 |
| MCF7 | PF477736 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 2979 | 5667 | 0.5257 | 0.3717 |
| MCF7 | PF562271 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 4397 | 5667 | 0.7758 | 0.7031 |
| MCF7 | PHA-665752 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 6367 | 5667 | 1.1233 | 1.1634 |
| MCF7 | PHA-793887 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 2180 | 5667 | 0.3847 | 0.1849 |
| MCF7 | PI103 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 2880 | 5667 | 0.5081 | 0.3484 |
| MCF7 | PLX-4720 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5721 | 5667 | 1.0095 | 1.0125 |
| MCF7 | QL-X-138 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 3314 | 5667 | 0.5848 | 0.4500 |
| MCF7 | QL-XII-47 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 3723 | 5667 | 0.6570 | 0.5456 |
| MCF7 | Radicicol | 0.12 | uM | LJP5 | 72 | hr | 1389 | 2459 | 5667 | 0.4339 | 0.2501 |