LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PI103 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1305 | 5667 | 0.2303 | -0.0196 |
| MCF7 | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5989 | 5667 | 1.0567 | 1.0750 |
| MCF7 | QL-X-138 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 2395 | 5667 | 0.4227 | 0.2353 |
| MCF7 | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1257 | 5667 | 0.2218 | -0.0309 |
| MCF7 | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1673 | 5667 | 0.2953 | 0.0665 |
| MCF7 | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1783 | 5667 | 0.3146 | 0.0921 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5276 | 5667 | 0.9309 | 0.9084 |
| MCF7 | Ruxolitinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 6306 | 5667 | 1.1127 | 1.1492 |
| MCF7 | XL147 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 6175 | 5667 | 1.0896 | 1.1186 |
| MCF7 | Saracatinib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1811 | 5667 | 0.3196 | 0.0987 |
| MCF7 | Selumetinib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 3004 | 5667 | 0.5300 | 0.3774 |
| MCF7 | Sirolimus | 1.11 | uM | LJP6 | 72 | hr | 1389 | 3115 | 5667 | 0.5496 | 0.4034 |
| MCF7 | Sorafenib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 4660 | 5667 | 0.8222 | 0.7645 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 4937 | 5667 | 0.8710 | 0.8292 |
| MCF7 | Fedratinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 4729 | 5667 | 0.8344 | 0.7806 |
| MCF7 | TGX221 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 6009 | 5667 | 1.0602 | 1.0797 |
| MCF7 | Torin1 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1569 | 5667 | 0.2769 | 0.0422 |
| MCF7 | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1352 | 5667 | 0.2386 | -0.0085 |
| MCF7 | Tozasertib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1626 | 5667 | 0.2870 | 0.0555 |
| MCF7 | Trametinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 2616 | 5667 | 0.4616 | 0.2869 |
| MCF7 | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 6210 | 5667 | 1.0957 | 1.1268 |
| MCF7 | Vemurafenib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 6263 | 5667 | 1.1050 | 1.1391 |
| MCF7 | Withaferin A | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1758 | 5667 | 0.3103 | 0.0863 |
| MCF7 | Withaferin A | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1678 | 5667 | 0.2961 | 0.0676 |
| MCF7 | WYE-125132 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1894 | 5667 | 0.3343 | 0.1182 |