LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | WZ3105 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 577 | 5667 | 0.1018 | -0.1898 |
| MCF7 | XMD11-50 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 2574 | 5667 | 0.4543 | 0.2771 |
| MCF7 | Y39983 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 5014 | 5667 | 0.8848 | 0.8473 |
| MCF7 | YM 201636 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 3887 | 5667 | 0.6859 | 0.5839 |
| MCF7 | ZSTK474 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1689 | 5667 | 0.2980 | 0.0701 |
| MCF7 | Afatinib | 3.33 | uM | LJP6 | 72 | hr | 1389 | 3759 | 5667 | 0.6632 | 0.5539 |
| MCF7 | Sigma A6730 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 3455 | 5667 | 0.6096 | 0.4828 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 1389 | 468 | 5667 | 0.0826 | -0.2153 |
| MCF7 | AT-7519 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 479 | 5667 | 0.0846 | -0.2126 |
| MCF7 | AZD 5438 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 688 | 5667 | 0.1215 | -0.1637 |
| MCF7 | AZD-6482 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 4380 | 5667 | 0.7728 | 0.6990 |
| MCF7 | AZD7762 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 1098 | 5667 | 0.1938 | -0.0679 |
| MCF7 | AZD8055 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 1413 | 5667 | 0.2493 | 0.0056 |
| MCF7 | AZD8330 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 2688 | 5667 | 0.4743 | 0.3037 |
| MCF7 | Barasertib | 3.33 | uM | LJP5 | 72 | hr | 1389 | 1739 | 5667 | 0.3068 | 0.0818 |
| MCF7 | BI-2536 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 1341 | 5667 | 0.2366 | -0.0112 |
| MCF7 | BMS345541 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 1593 | 5667 | 0.2812 | 0.0478 |
| MCF7 | SNS-032 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 522 | 5667 | 0.0922 | -0.2026 |
| MCF7 | GDC-0980 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 1389 | 5667 | 0.2452 | 0.0001 |
| MCF7 | NVP-AEW541 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 3185 | 5667 | 0.5620 | 0.4198 |
| MCF7 | SB590885 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 6498 | 5667 | 1.1465 | 1.1941 |
| MCF7 | PIK-93 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 3444 | 5667 | 0.6076 | 0.4803 |
| MCF7 | KIN001-043 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 4548 | 5667 | 0.8024 | 0.7383 |
| MCF7 | Alpelisib | 3.33 | uM | LJP5 | 72 | hr | 1389 | 2436 | 5667 | 0.4298 | 0.2447 |
| MCF7 | Luminespib | 3.33 | uM | LJP5 | 72 | hr | 1389 | 1467 | 5667 | 0.2589 | 0.0183 |