LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 SB590885
0.04
uM
LJP5
 72
hr
 1311 5029 5013 1.0032 1.0043
MDA-MB-231 PIK-93
0.04
uM
LJP5
 72
hr
 1311 5214 5013 1.0401 1.0543
MDA-MB-231 KIN001-043
0.04
uM
LJP6
 72
hr
 1311 4772 5013 0.9518 0.9348
MDA-MB-231 Alpelisib
0.04
uM
LJP5
 72
hr
 1311 5183 5013 1.0339 1.0460
MDA-MB-231 Luminespib
0.04
uM
LJP5
 72
hr
 1311 1013 5013 0.2021 -0.0806
MDA-MB-231 A443654
0.04
uM
LJP6
 72
hr
 1311 3906 5013 0.7791 0.7008
MDA-MB-231 OSI-027
0.04
uM
LJP6
 72
hr
 1311 5123 5013 1.0218 1.0296
MDA-MB-231 XMD11-85h
0.04
uM
LJP6
 72
hr
 1311 3815 5013 0.7609 0.6762
MDA-MB-231 HG-6-64-01
0.04
uM
LJP6
 72
hr
 1311 4569 5013 0.9115 0.8801
MDA-MB-231 WH-4-025
0.04
uM
LJP5
 72
hr
 1311 4389 5013 0.8755 0.8314
MDA-MB-231 WZ-4-145
0.04
uM
LJP6
 72
hr
 1311 4364 5013 0.8705 0.8246
MDA-MB-231 XMD16-144
0.04
uM
LJP5
 72
hr
 1311 2681 5013 0.5348 0.3699
MDA-MB-231 Brivanib
0.04
uM
LJP5
 72
hr
 1311 5226 5013 1.0424 1.0574
MDA-MB-231 Buparlisib
0.04
uM
LJP5
 72
hr
 1311 5265 5013 1.0502 1.0679
MDA-MB-231 BX-912
0.04
uM
LJP5
 72
hr
 1311 4614 5013 0.9203 0.8921
MDA-MB-231 Canertinib
0.04
uM
LJP6
 72
hr
 1311 5102 5013 1.0178 1.0241
MDA-MB-231 Celastrol
0.04
uM
LJP6
 72
hr
 1311 5141 5013 1.0254 1.0344
MDA-MB-231 CGP60474
0.04
uM
LJP5
 72
hr
 1311 3853 5013 0.7685 0.6865
MDA-MB-231 CGP60474
0.04
uM
LJP6
 72
hr
 1311 927 5013 0.1850 -0.1038
MDA-MB-231 CHIR-99021
0.04
uM
LJP6
 72
hr
 1311 4664 5013 0.9304 0.9057
MDA-MB-231 CP724714
0.04
uM
LJP5
 72
hr
 1311 4619 5013 0.9214 0.8936
MDA-MB-231 CP466722
0.04
uM
LJP5
 72
hr
 1311 5276 5013 1.0524 1.0710
MDA-MB-231 Crizotinib
0.04
uM
LJP5
 72
hr
 1311 4251 5013 0.8480 0.7941
MDA-MB-231 Momelotinib
0.04
uM
LJP5
 72
hr
 1311 4666 5013 0.9307 0.9061
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 72
hr
 1311 2371 5013 0.4731 0.2863