LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 CP724714
0.37
uM
LJP5
 72
hr
 1311 4803 5013 0.9581 0.9432
MDA-MB-231 CP466722
0.37
uM
LJP5
 72
hr
 1311 5060 5013 1.0093 1.0126
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 72
hr
 1311 4136 5013 0.8250 0.7630
MDA-MB-231 Momelotinib
0.37
uM
LJP5
 72
hr
 1311 3767 5013 0.7514 0.6633
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 72
hr
 1311 927 5013 0.1849 -0.1039
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 72
hr
 1311 916 5013 0.1828 -0.1067
MDA-MB-231 Dovitinib
0.37
uM
LJP5
 72
hr
 1311 3488 5013 0.6957 0.5879
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 72
hr
 1311 4838 5013 0.9651 0.9527
MDA-MB-231 Erlotinib
0.37
uM
LJP5
 72
hr
 1311 5018 5013 1.0010 1.0014
MDA-MB-231 Foretinib
0.37
uM
LJP5
 72
hr
 1311 1692 5013 0.3376 0.1028
MDA-MB-231 R406
0.37
uM
LJP6
 72
hr
 1311 4396 5013 0.8769 0.8333
MDA-MB-231 Pictilisib
0.37
uM
LJP6
 72
hr
 1311 3718 5013 0.7417 0.6501
MDA-MB-231 Gefitinib
0.37
uM
LJP6
 72
hr
 1311 5011 5013 0.9996 0.9995
MDA-MB-231 Geldanamycin
0.37
uM
LJP5
 72
hr
 1311 1282 5013 0.2557 -0.0080
MDA-MB-231 Geldanamycin
0.37
uM
LJP6
 72
hr
 1311 1247 5013 0.2487 -0.0175
MDA-MB-231 GSK1059615
0.37
uM
LJP5
 72
hr
 1311 4830 5013 0.9635 0.9506
MDA-MB-231 GSK1059615
0.37
uM
LJP6
 72
hr
 1311 4887 5013 0.9749 0.9660
MDA-MB-231 GSK1904529A
0.37
uM
LJP6
 72
hr
 1311 4427 5013 0.8831 0.8417
MDA-MB-231 Omipalisib
0.37
uM
LJP6
 72
hr
 1311 1528 5013 0.3048 0.0584
MDA-MB-231 GSK 690693
0.37
uM
LJP5
 72
hr
 1311 4632 5013 0.9240 0.8971
MDA-MB-231 GW843682X
0.37
uM
LJP6
 72
hr
 1311 3026 5013 0.6036 0.4631
MDA-MB-231 HG-5-113-01
0.37
uM
LJP5
 72
hr
 1311 4160 5013 0.8299 0.7696
MDA-MB-231 HG-5-88-01
0.37
uM
LJP6
 72
hr
 1311 4245 5013 0.8467 0.7924
MDA-MB-231 Imatinib
0.37
uM
LJP6
 72
hr
 1311 4897 5013 0.9768 0.9686
MDA-MB-231 JNK-9L
0.37
uM
LJP6
 72
hr
 1311 2934 5013 0.5852 0.4382