LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 GW843682X
3.33
uM
LJP6
 72
hr
 1311 1202 5013 0.2398 -0.0296
MDA-MB-231 HG-5-113-01
3.33
uM
LJP5
 72
hr
 1311 1817 5013 0.3625 0.1366
MDA-MB-231 HG-5-88-01
3.33
uM
LJP6
 72
hr
 1311 4300 5013 0.8578 0.8073
MDA-MB-231 Imatinib
3.33
uM
LJP6
 72
hr
 1311 5047 5013 1.0067 1.0090
MDA-MB-231 JNK-9L
3.33
uM
LJP6
 72
hr
 1311 1100 5013 0.2194 -0.0572
MDA-MB-231 JW-7-24-1
3.33
uM
LJP6
 72
hr
 1311 3476 5013 0.6935 0.5848
MDA-MB-231 Lapatinib
3.33
uM
LJP6
 72
hr
 1311 4638 5013 0.9252 0.8987
MDA-MB-231 LDN-193189
3.33
uM
LJP5
 72
hr
 1311 2529 5013 0.5046 0.3290
MDA-MB-231 Linifanib
3.33
uM
LJP6
 72
hr
 1311 4959 5013 0.9892 0.9854
MDA-MB-231 Linsitinib
3.33
uM
LJP5
 72
hr
 1311 4742 5013 0.9458 0.9267
MDA-MB-231 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1311 865 5013 0.1727 -0.1205
MDA-MB-231 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1311 746 5013 0.1488 -0.1528
MDA-MB-231 MK2206
3.33
uM
LJP6
 72
hr
 1311 4082 5013 0.8142 0.7484
MDA-MB-231 Neratinib
3.33
uM
LJP5
 72
hr
 1311 3674 5013 0.7328 0.6381
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 72
hr
 1311 4618 5013 0.9212 0.8933
MDA-MB-231 Nintedanib
3.33
uM
LJP6
 72
hr
 1311 4618 5013 0.9212 0.8932
MDA-MB-231 NU7441
3.33
uM
LJP5
 72
hr
 1311 3739 5013 0.7459 0.6559
MDA-MB-231 Dactolisib
3.33
uM
LJP5
 72
hr
 1311 2071 5013 0.4132 0.2052
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 72
hr
 1311 1462 5013 0.2917 0.0407
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 72
hr
 1311 2426 5013 0.4839 0.3010
MDA-MB-231 PD0325901
3.33
uM
LJP5
 72
hr
 1311 1494 5013 0.2980 0.0492
MDA-MB-231 PD0325901
3.33
uM
LJP6
 72
hr
 1311 1276 5013 0.2545 -0.0096
MDA-MB-231 PD173074
3.33
uM
LJP6
 72
hr
 1311 5152 5013 1.0278 1.0376
MDA-MB-231 PD184352
3.33
uM
LJP5
 72
hr
 1311 2896 5013 0.5778 0.4282
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 72
hr
 1311 2847 5013 0.5679 0.4148