LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 JW-7-24-1
0.37
uM
LJP6
 72
hr
 1311 4183 5013 0.8343 0.7756
MDA-MB-231 Lapatinib
0.37
uM
LJP6
 72
hr
 1311 4748 5013 0.9470 0.9283
MDA-MB-231 LDN-193189
0.37
uM
LJP5
 72
hr
 1311 4623 5013 0.9222 0.8946
MDA-MB-231 Linifanib
0.37
uM
LJP6
 72
hr
 1311 5129 5013 1.0230 1.0312
MDA-MB-231 Linsitinib
0.37
uM
LJP5
 72
hr
 1311 4864 5013 0.9702 0.9596
MDA-MB-231 Mitoxantrone
0.37
uM
LJP5
 72
hr
 1311 1009 5013 0.2014 -0.0816
MDA-MB-231 Mitoxantrone
0.37
uM
LJP6
 72
hr
 1311 992 5013 0.1979 -0.0863
MDA-MB-231 MK2206
0.37
uM
LJP6
 72
hr
 1311 4166 5013 0.8310 0.7711
MDA-MB-231 Neratinib
0.37
uM
LJP5
 72
hr
 1311 4362 5013 0.8701 0.8241
MDA-MB-231 Nilotinib
0.37
uM
LJP5
 72
hr
 1311 4736 5013 0.9446 0.9250
MDA-MB-231 Nintedanib
0.37
uM
LJP6
 72
hr
 1311 4883 5013 0.9741 0.9649
MDA-MB-231 NU7441
0.37
uM
LJP5
 72
hr
 1311 4539 5013 0.9054 0.8719
MDA-MB-231 Dactolisib
0.37
uM
LJP5
 72
hr
 1311 2036 5013 0.4062 0.1958
MDA-MB-231 NVP-TAE684
0.37
uM
LJP6
 72
hr
 1311 3917 5013 0.7813 0.7038
MDA-MB-231 Palbociclib
0.37
uM
LJP6
 72
hr
 1311 2996 5013 0.5976 0.4550
MDA-MB-231 PD0325901
0.37
uM
LJP5
 72
hr
 1311 2182 5013 0.4354 0.2353
MDA-MB-231 PD0325901
0.37
uM
LJP6
 72
hr
 1311 2062 5013 0.4113 0.2027
MDA-MB-231 PD173074
0.37
uM
LJP6
 72
hr
 1311 5192 5013 1.0357 1.0484
MDA-MB-231 PD184352
0.37
uM
LJP5
 72
hr
 1311 4016 5013 0.8011 0.7306
MDA-MB-231 Pelitinib
0.37
uM
LJP5
 72
hr
 1311 4647 5013 0.9270 0.9012
MDA-MB-231 PF431396
0.37
uM
LJP5
 72
hr
 1311 3285 5013 0.6552 0.5331
MDA-MB-231 PF477736
0.37
uM
LJP5
 72
hr
 1311 4546 5013 0.9068 0.8737
MDA-MB-231 PF562271
0.37
uM
LJP6
 72
hr
 1311 3973 5013 0.7925 0.7189
MDA-MB-231 PHA-665752
0.37
uM
LJP5
 72
hr
 1311 5000 5013 0.9974 0.9964
MDA-MB-231 PHA-793887
0.37
uM
LJP6
 72
hr
 1311 1482 5013 0.2957 0.0462