LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Dasatinib
0.04
uM
LJP6
72
hr
1311 1256 5013 0.2506 -0.0150
MDA-MB-231 Dovitinib
0.04
uM
LJP5
72
hr
1311 4858 5013 0.9690 0.9580
MDA-MB-231 Enzastaurin
0.04
uM
LJP5
72
hr
1311 4962 5013 0.9899 0.9863
MDA-MB-231 Erlotinib
0.04
uM
LJP5
72
hr
1311 4853 5013 0.9681 0.9567
MDA-MB-231 Foretinib
0.04
uM
LJP5
72
hr
1311 4473 5013 0.8923 0.8542
MDA-MB-231 R406
0.04
uM
LJP6
72
hr
1311 4938 5013 0.9849 0.9796
MDA-MB-231 Pictilisib
0.04
uM
LJP6
72
hr
1311 4066 5013 0.8110 0.7440
MDA-MB-231 Gefitinib
0.04
uM
LJP6
72
hr
1311 5117 5013 1.0207 1.0280
MDA-MB-231 Geldanamycin
0.04
uM
LJP5
72
hr
1311 3731 5013 0.7443 0.6536
MDA-MB-231 Geldanamycin
0.04
uM
LJP6
72
hr
1311 3430 5013 0.6842 0.5723
MDA-MB-231 GSK1059615
0.04
uM
LJP5
72
hr
1311 5134 5013 1.0240 1.0325
MDA-MB-231 GSK1059615
0.04
uM
LJP6
72
hr
1311 5133 5013 1.0240 1.0325
MDA-MB-231 GSK1904529A
0.04
uM
LJP6
72
hr
1311 4224 5013 0.8425 0.7867
MDA-MB-231 Omipalisib
0.04
uM
LJP6
72
hr
1311 3047 5013 0.6079 0.4690
MDA-MB-231 GSK 690693
0.04
uM
LJP5
72
hr
1311 4763 5013 0.9500 0.9323
MDA-MB-231 GW843682X
0.04
uM
LJP6
72
hr
1311 4692 5013 0.9359 0.9132
MDA-MB-231 HG-5-113-01
0.04
uM
LJP5
72
hr
1311 4993 5013 0.9960 0.9946
MDA-MB-231 HG-5-88-01
0.04
uM
LJP6
72
hr
1311 4077 5013 0.8133 0.7471
MDA-MB-231 Imatinib
0.04
uM
LJP6
72
hr
1311 4853 5013 0.9680 0.9566
MDA-MB-231 JNK-9L
0.04
uM
LJP6
72
hr
1311 4136 5013 0.8250 0.7630
MDA-MB-231 JW-7-24-1
0.04
uM
LJP6
72
hr
1311 4188 5013 0.8355 0.7772
MDA-MB-231 Lapatinib
0.04
uM
LJP6
72
hr
1311 4495 5013 0.8967 0.8601
MDA-MB-231 LDN-193189
0.04
uM
LJP5
72
hr
1311 4869 5013 0.9712 0.9610
MDA-MB-231 Linifanib
0.04
uM
LJP6
72
hr
1311 5333 5013 1.0639 1.0865
MDA-MB-231 Linsitinib
0.04
uM
LJP5
72
hr
1311 4312 5013 0.8601 0.8106