LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Mitoxantrone
0.04
uM
LJP5
 72
hr
 1311 1185 5013 0.2364 -0.0342
MDA-MB-231 Mitoxantrone
0.04
uM
LJP6
 72
hr
 1311 1081 5013 0.2158 -0.0621
MDA-MB-231 MK2206
0.04
uM
LJP6
 72
hr
 1311 4932 5013 0.9837 0.9780
MDA-MB-231 Neratinib
0.04
uM
LJP5
 72
hr
 1311 4830 5013 0.9634 0.9504
MDA-MB-231 Nilotinib
0.04
uM
LJP5
 72
hr
 1311 4981 5013 0.9935 0.9912
MDA-MB-231 Nintedanib
0.04
uM
LJP6
 72
hr
 1311 5178 5013 1.0329 1.0446
MDA-MB-231 NU7441
0.04
uM
LJP5
 72
hr
 1311 4964 5013 0.9901 0.9866
MDA-MB-231 Dactolisib
0.04
uM
LJP5
 72
hr
 1311 2836 5013 0.5657 0.4119
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 72
hr
 1311 4655 5013 0.9285 0.9032
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 72
hr
 1311 3634 5013 0.7250 0.6275
MDA-MB-231 PD0325901
0.04
uM
LJP5
 72
hr
 1311 3265 5013 0.6513 0.5278
MDA-MB-231 PD0325901
0.04
uM
LJP6
 72
hr
 1311 3157 5013 0.6298 0.4987
MDA-MB-231 PD173074
0.04
uM
LJP6
 72
hr
 1311 5128 5013 1.0230 1.0311
MDA-MB-231 PD184352
0.04
uM
LJP5
 72
hr
 1311 5023 5013 1.0020 1.0027
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 72
hr
 1311 5209 5013 1.0391 1.0529
MDA-MB-231 PF431396
0.04
uM
LJP5
 72
hr
 1311 4596 5013 0.9169 0.8874
MDA-MB-231 PF477736
0.04
uM
LJP5
 72
hr
 1311 4702 5013 0.9380 0.9160
MDA-MB-231 PF562271
0.04
uM
LJP6
 72
hr
 1311 4542 5013 0.9060 0.8726
MDA-MB-231 PHA-665752
0.04
uM
LJP5
 72
hr
 1311 4957 5013 0.9887 0.9847
MDA-MB-231 PHA-793887
0.04
uM
LJP6
 72
hr
 1311 2323 5013 0.4635 0.2734
MDA-MB-231 PI103
0.04
uM
LJP6
 72
hr
 1311 4162 5013 0.8302 0.7701
MDA-MB-231 PLX-4720
0.04
uM
LJP5
 72
hr
 1311 5160 5013 1.0293 1.0397
MDA-MB-231 QL-X-138
0.04
uM
LJP6
 72
hr
 1311 4357 5013 0.8692 0.8228
MDA-MB-231 QL-XII-47
0.04
uM
LJP6
 72
hr
 1311 3981 5013 0.7941 0.7211
MDA-MB-231 Radicicol
0.04
uM
LJP5
 72
hr
 1311 5349 5013 1.0670 1.0907