LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Radicicol | 0.12 | uM | LJP6 | 72 | hr | 1389 | 2238 | 5667 | 0.3949 | 0.1985 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5970 | 5667 | 1.0533 | 1.0706 |
| MCF7 | Ruxolitinib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5443 | 5667 | 0.9604 | 0.9476 |
| MCF7 | XL147 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 6374 | 5667 | 1.1247 | 1.1651 |
| MCF7 | Saracatinib | 0.12 | uM | LJP6 | 72 | hr | 1389 | 3378 | 5667 | 0.5961 | 0.4650 |
| MCF7 | Selumetinib | 0.12 | uM | LJP6 | 72 | hr | 1389 | 4127 | 5667 | 0.7283 | 0.6400 |
| MCF7 | Sirolimus | 0.12 | uM | LJP6 | 72 | hr | 1389 | 3177 | 5667 | 0.5606 | 0.4179 |
| MCF7 | Sorafenib | 0.12 | uM | LJP6 | 72 | hr | 1389 | 4987 | 5667 | 0.8799 | 0.8409 |
| MCF7 | SU11274 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5985 | 5667 | 1.0560 | 1.0742 |
| MCF7 | Fedratinib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 6029 | 5667 | 1.0637 | 1.0844 |
| MCF7 | TGX221 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5067 | 5667 | 0.8940 | 0.8596 |
| MCF7 | Torin1 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 1804 | 5667 | 0.3183 | 0.0970 |
| MCF7 | Torin2 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 1641 | 5667 | 0.2896 | 0.0590 |
| MCF7 | Tozasertib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 1514 | 5667 | 0.2672 | 0.0293 |
| MCF7 | Trametinib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 2715 | 5667 | 0.4790 | 0.3099 |
| MCF7 | TWS119 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 6153 | 5667 | 1.0856 | 1.1134 |
| MCF7 | Vemurafenib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5909 | 5667 | 1.0425 | 1.0563 |
| MCF7 | Withaferin A | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5397 | 5667 | 0.9522 | 0.9367 |
| MCF7 | Withaferin A | 0.12 | uM | LJP6 | 72 | hr | 1389 | 5200 | 5667 | 0.9175 | 0.8907 |
| MCF7 | WYE-125132 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 1919 | 5667 | 0.3386 | 0.1239 |
| MCF7 | WZ3105 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 485 | 5667 | 0.0857 | -0.2112 |
| MCF7 | XMD11-50 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 4496 | 5667 | 0.7933 | 0.7262 |
| MCF7 | Y39983 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 5459 | 5667 | 0.9633 | 0.9513 |
| MCF7 | YM 201636 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5685 | 5667 | 1.0030 | 1.0040 |
| MCF7 | ZSTK474 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 3157 | 5667 | 0.5571 | 0.4133 |