LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Nintedanib | 10.0 | uM | LJP6 | 72 | hr | 1694 | 10976 | 11155 | 0.9839 | 0.9811 |
| MCF 10A | NU7441 | 10.0 | uM | LJP5 | 72 | hr | 1694 | 7207 | 11155 | 0.6460 | 0.5827 |
| MCF 10A | Dactolisib | 10.0 | uM | LJP5 | 72 | hr | 1694 | 2976 | 11155 | 0.2668 | 0.1355 |
| MCF 10A | NVP-TAE684 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 2966 | 11155 | 0.2659 | 0.1345 |
| MCF 10A | Palbociclib | 10.0 | uM | LJP6 | 72 | hr | 1694 | 4663 | 11155 | 0.4180 | 0.3138 |
| MCF 10A | PD0325901 | 10.0 | uM | LJP5 | 72 | hr | 1694 | 2253 | 11155 | 0.2020 | 0.0591 |
| MCF 10A | PD0325901 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 1942 | 11155 | 0.1741 | 0.0262 |
| MCF 10A | PD173074 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 6577 | 11155 | 0.5896 | 0.5161 |
| MCF 10A | PD184352 | 10.0 | uM | LJP5 | 72 | hr | 1694 | 3034 | 11155 | 0.2720 | 0.1417 |
| MCF 10A | Pelitinib | 10.0 | uM | LJP5 | 72 | hr | 1694 | 1782 | 11155 | 0.1598 | 0.0093 |
| MCF 10A | PF431396 | 10.0 | uM | LJP5 | 72 | hr | 1694 | 714 | 11155 | 0.0640 | -0.1036 |
| MCF 10A | PF477736 | 10.0 | uM | LJP5 | 72 | hr | 1694 | 1333 | 11155 | 0.1196 | -0.0381 |
| MCF 10A | PF562271 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 494 | 11155 | 0.0443 | -0.1269 |
| MCF 10A | PHA-665752 | 10.0 | uM | LJP5 | 72 | hr | 1694 | 9302 | 11155 | 0.8339 | 0.8041 |
| MCF 10A | PHA-793887 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 558 | 11155 | 0.0500 | -0.1201 |
| MCF 10A | PI103 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 2227 | 11155 | 0.1996 | 0.0563 |
| MCF 10A | PLX-4720 | 10.0 | uM | LJP5 | 72 | hr | 1694 | 10314 | 11155 | 0.9246 | 0.9111 |
| MCF 10A | QL-X-138 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 1170 | 11155 | 0.1049 | -0.0553 |
| MCF 10A | QL-XII-47 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 806 | 11155 | 0.0723 | -0.0938 |
| MCF 10A | Radicicol | 10.0 | uM | LJP5 | 72 | hr | 1694 | 602 | 11155 | 0.0540 | -0.1154 |
| MCF 10A | Radicicol | 10.0 | uM | LJP6 | 72 | hr | 1694 | 839 | 11155 | 0.0753 | -0.0903 |
| MCF 10A | Seliciclib | 10.0 | uM | LJP5 | 72 | hr | 1694 | 4986 | 11155 | 0.4470 | 0.3479 |
| MCF 10A | Ruxolitinib | 10.0 | uM | LJP5 | 72 | hr | 1694 | 9296 | 11155 | 0.8333 | 0.8035 |
| MCF 10A | XL147 | 10.0 | uM | LJP5 | 72 | hr | 1694 | 5776 | 11155 | 0.5178 | 0.4314 |
| MCF 10A | Saracatinib | 10.0 | uM | LJP6 | 72 | hr | 1694 | 2446 | 11155 | 0.2193 | 0.0795 |