LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 Afatinib
0.37
uM
LJP6
 72
hr
 1389 4933 5667 0.8705 0.8284
MCF7 Sigma A6730
0.37
uM
LJP5
 72
hr
 1389 4775 5667 0.8426 0.7914
MCF7 Alvocidib
0.37
uM
LJP6
 72
hr
 1389 489 5667 0.0863 -0.2104
MCF7 AT-7519
0.37
uM
LJP6
 72
hr
 1389 755 5667 0.1333 -0.1480
MCF7 AZD 5438
0.37
uM
LJP6
 72
hr
 1389 1573 5667 0.2777 0.0431
MCF7 AZD-6482
0.37
uM
LJP5
 72
hr
 1389 6318 5667 1.1147 1.1519
MCF7 AZD7762
0.37
uM
LJP6
 72
hr
 1389 1519 5667 0.2681 0.0304
MCF7 AZD8055
0.37
uM
LJP6
 72
hr
 1389 1451 5667 0.2561 0.0146
MCF7 AZD8330
0.37
uM
LJP5
 72
hr
 1389 2405 5667 0.4243 0.2374
MCF7 Barasertib
0.37
uM
LJP5
 72
hr
 1389 1687 5667 0.2977 0.0697
MCF7 BI-2536
0.37
uM
LJP6
 72
hr
 1389 1446 5667 0.2552 0.0134
MCF7 BMS345541
0.37
uM
LJP6
 72
hr
 1389 4997 5667 0.8818 0.8434
MCF7 SNS-032
0.37
uM
LJP6
 72
hr
 1389 565 5667 0.0997 -0.1926
MCF7 GDC-0980
0.37
uM
LJP5
 72
hr
 1389 1360 5667 0.2400 -0.0067
MCF7 NVP-AEW541
0.37
uM
LJP5
 72
hr
 1389 3387 5667 0.5976 0.4669
MCF7 SB590885
0.37
uM
LJP5
 72
hr
 1389 5754 5667 1.0153 1.0202
MCF7 PIK-93
0.37
uM
LJP5
 72
hr
 1389 6152 5667 1.0855 1.1133
MCF7 KIN001-043
0.37
uM
LJP6
 72
hr
 1389 4541 5667 0.8012 0.7367
MCF7 Alpelisib
0.37
uM
LJP5
 72
hr
 1389 3867 5667 0.6824 0.5792
MCF7 Luminespib
0.37
uM
LJP5
 72
hr
 1389 1368 5667 0.2414 -0.0049
MCF7 A443654
0.37
uM
LJP6
 72
hr
 1389 886 5667 0.1563 -0.1176
MCF7 OSI-027
0.37
uM
LJP6
 72
hr
 1389 2848 5667 0.5026 0.3411
MCF7 XMD11-85h
0.37
uM
LJP6
 72
hr
 1389 4413 5667 0.7786 0.7067
MCF7 HG-6-64-01
0.37
uM
LJP6
 72
hr
 1389 5714 5667 1.0082 1.0109
MCF7 WH-4-025
0.37
uM
LJP5
 72
hr
 1389 3583 5667 0.6322 0.5127