LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T PD0325901
3.33
uM
LJP5
 72
hr
 765 877 3124 0.2807 0.0474
Hs 578T PD0325901
3.33
uM
LJP6
 72
hr
 765 831 3124 0.2660 0.0280
Hs 578T PD173074
3.33
uM
LJP6
 72
hr
 765 2334 3124 0.7470 0.6650
Hs 578T PD184352
3.33
uM
LJP5
 72
hr
 765 1573 3124 0.5034 0.3424
Hs 578T Pelitinib
3.33
uM
LJP5
 72
hr
 765 2021 3124 0.6470 0.5326
Hs 578T PF431396
3.33
uM
LJP5
 72
hr
 765 921 3124 0.2948 0.0661
Hs 578T PF477736
3.33
uM
LJP5
 72
hr
 765 532 3124 0.1705 -0.0985
Hs 578T PF562271
3.33
uM
LJP6
 72
hr
 765 1526 3124 0.4885 0.3227
Hs 578T PHA-665752
3.33
uM
LJP5
 72
hr
 765 2945 3124 0.9425 0.9239
Hs 578T PHA-793887
3.33
uM
LJP6
 72
hr
 765 619 3124 0.1982 -0.0618
Hs 578T PI103
3.33
uM
LJP6
 72
hr
 765 709 3124 0.2269 -0.0238
Hs 578T PLX-4720
3.33
uM
LJP5
 72
hr
 765 3306 3124 1.0583 1.0772
Hs 578T QL-X-138
3.33
uM
LJP6
 72
hr
 765 1463 3124 0.4683 0.2960
Hs 578T QL-XII-47
3.33
uM
LJP6
 72
hr
 765 1207 3124 0.3864 0.1875
Hs 578T Radicicol
3.33
uM
LJP5
 72
hr
 765 920 3124 0.2947 0.0660
Hs 578T Radicicol
3.33
uM
LJP6
 72
hr
 765 865 3124 0.2768 0.0424
Hs 578T Seliciclib
3.33
uM
LJP5
 72
hr
 765 3092 3124 0.9898 0.9865
Hs 578T Ruxolitinib
3.33
uM
LJP5
 72
hr
 765 2778 3124 0.8892 0.8533
Hs 578T XL147
3.33
uM
LJP5
 72
hr
 765 2876 3124 0.9207 0.8950
Hs 578T Saracatinib
3.33
uM
LJP6
 72
hr
 765 1957 3124 0.6264 0.5053
Hs 578T Selumetinib
3.33
uM
LJP6
 72
hr
 765 1361 3124 0.4356 0.2526
Hs 578T Sirolimus
3.33
uM
LJP6
 72
hr
 765 1851 3124 0.5926 0.4605
Hs 578T Sorafenib
3.33
uM
LJP6
 72
hr
 765 3770 3124 1.2066 1.2736
Hs 578T SU11274
3.33
uM
LJP5
 72
hr
 765 2548 3124 0.8157 0.7559
Hs 578T Fedratinib
3.33
uM
LJP5
 72
hr
 765 1001 3124 0.3204 0.1000