LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T PF431396
0.37
uM
LJP5
 72
hr
 765 1807 3124 0.5785 0.4419
Hs 578T PF477736
0.37
uM
LJP5
 72
hr
 765 797 3124 0.2552 0.0137
Hs 578T PF562271
0.37
uM
LJP6
 72
hr
 765 2251 3124 0.7205 0.6299
Hs 578T PHA-665752
0.37
uM
LJP5
 72
hr
 765 3114 3124 0.9967 0.9957
Hs 578T PHA-793887
0.37
uM
LJP6
 72
hr
 765 1113 3124 0.3564 0.1478
Hs 578T PI103
0.37
uM
LJP6
 72
hr
 765 968 3124 0.3099 0.0862
Hs 578T PLX-4720
0.37
uM
LJP5
 72
hr
 765 3751 3124 1.2006 1.2656
Hs 578T QL-X-138
0.37
uM
LJP6
 72
hr
 765 2050 3124 0.6563 0.5449
Hs 578T QL-XII-47
0.37
uM
LJP6
 72
hr
 765 2539 3124 0.8126 0.7518
Hs 578T Radicicol
0.37
uM
LJP5
 72
hr
 765 2518 3124 0.8059 0.7429
Hs 578T Radicicol
0.37
uM
LJP6
 72
hr
 765 2454 3124 0.7856 0.7161
Hs 578T Seliciclib
0.37
uM
LJP5
 72
hr
 765 3110 3124 0.9955 0.9940
Hs 578T Ruxolitinib
0.37
uM
LJP5
 72
hr
 765 3131 3124 1.0021 1.0027
Hs 578T XL147
0.37
uM
LJP5
 72
hr
 765 3091 3124 0.9894 0.9859
Hs 578T Saracatinib
0.37
uM
LJP6
 72
hr
 765 2654 3124 0.8494 0.8006
Hs 578T Selumetinib
0.37
uM
LJP6
 72
hr
 765 1601 3124 0.5125 0.3544
Hs 578T Sirolimus
0.37
uM
LJP6
 72
hr
 765 1904 3124 0.6095 0.4829
Hs 578T Sorafenib
0.37
uM
LJP6
 72
hr
 765 3768 3124 1.2059 1.2727
Hs 578T SU11274
0.37
uM
LJP5
 72
hr
 765 2978 3124 0.9531 0.9379
Hs 578T Fedratinib
0.37
uM
LJP5
 72
hr
 765 2853 3124 0.9131 0.8849
Hs 578T TGX221
0.37
uM
LJP5
 72
hr
 765 2818 3124 0.9019 0.8701
Hs 578T Torin1
0.37
uM
LJP6
 72
hr
 765 867 3124 0.2777 0.0435
Hs 578T Torin2
0.37
uM
LJP5
 72
hr
 765 575 3124 0.1842 -0.0803
Hs 578T Tozasertib
0.37
uM
LJP5
 72
hr
 765 768 3124 0.2458 0.0013
Hs 578T Trametinib
0.37
uM
LJP5
 72
hr
 765 1038 3124 0.3323 0.1158