LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T JW-7-24-1
0.04
uM
LJP6
 72
hr
 765 2902 3124 0.9288 0.9057
Hs 578T Lapatinib
0.04
uM
LJP6
 72
hr
 765 3101 3124 0.9926 0.9902
Hs 578T LDN-193189
0.04
uM
LJP5
 72
hr
 765 2907 3124 0.9305 0.9079
Hs 578T Linifanib
0.04
uM
LJP6
 72
hr
 765 3104 3124 0.9934 0.9913
Hs 578T Linsitinib
0.04
uM
LJP5
 72
hr
 765 3175 3124 1.0164 1.0217
Hs 578T Mitoxantrone
0.04
uM
LJP5
 72
hr
 765 836 3124 0.2678 0.0304
Hs 578T Mitoxantrone
0.04
uM
LJP6
 72
hr
 765 807 3124 0.2585 0.0181
Hs 578T MK2206
0.04
uM
LJP6
 72
hr
 765 2768 3124 0.8859 0.8489
Hs 578T Neratinib
0.04
uM
LJP5
 72
hr
 765 2797 3124 0.8954 0.8615
Hs 578T Nilotinib
0.04
uM
LJP5
 72
hr
 765 3536 3124 1.1318 1.1745
Hs 578T Nintedanib
0.04
uM
LJP6
 72
hr
 765 2816 3124 0.9013 0.8692
Hs 578T NU7441
0.04
uM
LJP5
 72
hr
 765 3059 3124 0.9792 0.9725
Hs 578T Dactolisib
0.04
uM
LJP5
 72
hr
 765 1114 3124 0.3566 0.1480
Hs 578T NVP-TAE684
0.04
uM
LJP6
 72
hr
 765 2879 3124 0.9214 0.8959
Hs 578T Palbociclib
0.04
uM
LJP6
 72
hr
 765 2272 3124 0.7273 0.6388
Hs 578T PD0325901
0.04
uM
LJP5
 72
hr
 765 1689 3124 0.5408 0.3919
Hs 578T PD0325901
0.04
uM
LJP6
 72
hr
 765 1638 3124 0.5245 0.3703
Hs 578T PD173074
0.04
uM
LJP6
 72
hr
 765 2421 3124 0.7751 0.7021
Hs 578T PD184352
0.04
uM
LJP5
 72
hr
 765 2390 3124 0.7649 0.6887
Hs 578T Pelitinib
0.04
uM
LJP5
 72
hr
 765 3131 3124 1.0022 1.0029
Hs 578T PF431396
0.04
uM
LJP5
 72
hr
 765 2369 3124 0.7582 0.6798
Hs 578T PF477736
0.04
uM
LJP5
 72
hr
 765 3009 3124 0.9632 0.9513
Hs 578T PF562271
0.04
uM
LJP6
 72
hr
 765 2769 3124 0.8862 0.8493
Hs 578T PHA-665752
0.04
uM
LJP5
 72
hr
 765 3047 3124 0.9752 0.9671
Hs 578T PHA-793887
0.04
uM
LJP6
 72
hr
 765 1590 3124 0.5090 0.3498