LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 Selumetinib
0.37
uM
LJP6
 72
hr
 1334 3848 3970 0.9692 0.9536
BT-20 Sirolimus
0.37
uM
LJP6
 72
hr
 1334 2491 3970 0.6273 0.4386
BT-20 Sorafenib
0.37
uM
LJP6
 72
hr
 1334 3601 3970 0.9068 0.8597
BT-20 SU11274
0.37
uM
LJP5
 72
hr
 1334 4098 3970 1.0321 1.0483
BT-20 Fedratinib
0.37
uM
LJP5
 72
hr
 1334 3888 3970 0.9793 0.9688
BT-20 TGX221
0.37
uM
LJP5
 72
hr
 1334 4135 3970 1.0415 1.0625
BT-20 Torin1
0.37
uM
LJP6
 72
hr
 1334 1429 3970 0.3600 0.0360
BT-20 Torin2
0.37
uM
LJP5
 72
hr
 1334 996 3970 0.2510 -0.1282
BT-20 Tozasertib
0.37
uM
LJP5
 72
hr
 1334 1075 3970 0.2708 -0.0984
BT-20 Trametinib
0.37
uM
LJP5
 72
hr
 1334 3392 3970 0.8543 0.7805
BT-20 TWS119
0.37
uM
LJP5
 72
hr
 1334 4111 3970 1.0353 1.0531
BT-20 Vemurafenib
0.37
uM
LJP5
 72
hr
 1334 3974 3970 1.0009 1.0013
BT-20 Withaferin A
0.37
uM
LJP5
 72
hr
 1334 2924 3970 0.7364 0.6030
BT-20 Withaferin A
0.37
uM
LJP6
 72
hr
 1334 3459 3970 0.8712 0.8059
BT-20 WYE-125132
0.37
uM
LJP6
 72
hr
 1334 1913 3970 0.4819 0.2196
BT-20 WZ3105
0.37
uM
LJP5
 72
hr
 1334 839 3970 0.2114 -0.1879
BT-20 XMD11-50
0.37
uM
LJP6
 72
hr
 1334 3824 3970 0.9631 0.9444
BT-20 Y39983
0.37
uM
LJP6
 72
hr
 1334 4100 3970 1.0325 1.0490
BT-20 YM 201636
0.37
uM
LJP5
 72
hr
 1334 3883 3970 0.9780 0.9669
BT-20 ZSTK474
0.37
uM
LJP6
 72
hr
 1334 3685 3970 0.9280 0.8916
BT-20 Afatinib
1.11
uM
LJP6
 72
hr
 1334 3442 3970 0.8670 0.7996
BT-20 Sigma A6730
1.11
uM
LJP5
 72
hr
 1334 3519 3970 0.8862 0.8286
BT-20 Alvocidib
1.11
uM
LJP6
 72
hr
 1334 370 3970 0.0932 -0.3659
BT-20 AT-7519
1.11
uM
LJP6
 72
hr
 1334 854 3970 0.2151 -0.1823
BT-20 AZD 5438
1.11
uM
LJP6
 72
hr
 1334 1736 3970 0.4374 0.1525