LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 1334 | 2794 | 3970 | 0.7036 | 0.5536 |
| BT-20 | AZD7762 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 2258 | 3970 | 0.5686 | 0.3502 |
| BT-20 | AZD8055 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 1506 | 3970 | 0.3794 | 0.0652 |
| BT-20 | AZD8330 | 1.11 | uM | LJP5 | 72 | hr | 1334 | 3298 | 3970 | 0.8305 | 0.7448 |
| BT-20 | Barasertib | 1.11 | uM | LJP5 | 72 | hr | 1334 | 1544 | 3970 | 0.3888 | 0.0794 |
| BT-20 | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 688 | 3970 | 0.1734 | -0.2451 |
| BT-20 | BMS345541 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 3750 | 3970 | 0.9445 | 0.9165 |
| BT-20 | SNS-032 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 423 | 3970 | 0.1065 | -0.3458 |
| BT-20 | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 1334 | 994 | 3970 | 0.2505 | -0.1290 |
| BT-20 | NVP-AEW541 | 1.11 | uM | LJP5 | 72 | hr | 1334 | 4177 | 3970 | 1.0520 | 1.0783 |
| BT-20 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1334 | 3956 | 3970 | 0.9963 | 0.9943 |
| BT-20 | PIK-93 | 1.11 | uM | LJP5 | 72 | hr | 1334 | 4128 | 3970 | 1.0397 | 1.0598 |
| BT-20 | KIN001-043 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 3446 | 3970 | 0.8678 | 0.8009 |
| BT-20 | Alpelisib | 1.11 | uM | LJP5 | 72 | hr | 1334 | 2990 | 3970 | 0.7531 | 0.6280 |
| BT-20 | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 1334 | 974 | 3970 | 0.2455 | -0.1366 |
| BT-20 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 1361 | 3970 | 0.3428 | 0.0101 |
| BT-20 | OSI-027 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 2706 | 3970 | 0.6815 | 0.5203 |
| BT-20 | XMD11-85h | 1.11 | uM | LJP6 | 72 | hr | 1334 | 4046 | 3970 | 1.0190 | 1.0286 |
| BT-20 | HG-6-64-01 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 3334 | 3970 | 0.8397 | 0.7585 |
| BT-20 | WH-4-025 | 1.11 | uM | LJP5 | 72 | hr | 1334 | 2011 | 3970 | 0.5064 | 0.2566 |
| BT-20 | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 3620 | 3970 | 0.9117 | 0.8670 |
| BT-20 | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 1334 | 1159 | 3970 | 0.2919 | -0.0666 |
| BT-20 | Brivanib | 1.11 | uM | LJP5 | 72 | hr | 1334 | 3891 | 3970 | 0.9800 | 0.9698 |
| BT-20 | Buparlisib | 1.11 | uM | LJP5 | 72 | hr | 1334 | 1273 | 3970 | 0.3207 | -0.0233 |
| BT-20 | BX-912 | 1.11 | uM | LJP5 | 72 | hr | 1334 | 3950 | 3970 | 0.9949 | 0.9923 |