LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | WZ-4-145 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 2361 | 3970 | 0.5947 | 0.3894 |
| BT-20 | XMD16-144 | 10.0 | uM | LJP5 | 72 | hr | 1334 | 818 | 3970 | 0.2062 | -0.1957 |
| BT-20 | Brivanib | 10.0 | uM | LJP5 | 72 | hr | 1334 | 3351 | 3970 | 0.8440 | 0.7650 |
| BT-20 | Buparlisib | 10.0 | uM | LJP5 | 72 | hr | 1334 | 463 | 3970 | 0.1166 | -0.3307 |
| BT-20 | BX-912 | 10.0 | uM | LJP5 | 72 | hr | 1334 | 1886 | 3970 | 0.4750 | 0.2093 |
| BT-20 | Canertinib | 10.0 | uM | LJP6 | 72 | hr | 1334 | 1300 | 3970 | 0.3275 | -0.0130 |
| BT-20 | Celastrol | 10.0 | uM | LJP6 | 72 | hr | 1334 | 570 | 3970 | 0.1436 | -0.2899 |
| BT-20 | CGP60474 | 10.0 | uM | LJP5 | 72 | hr | 1334 | 330 | 3970 | 0.0833 | -0.3809 |
| BT-20 | CGP60474 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 278 | 3970 | 0.0702 | -0.4006 |
| BT-20 | CHIR-99021 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 4018 | 3970 | 1.0119 | 1.0180 |
| BT-20 | CP724714 | 10.0 | uM | LJP5 | 72 | hr | 1334 | 2676 | 3970 | 0.6741 | 0.5091 |
| BT-20 | CP466722 | 10.0 | uM | LJP5 | 72 | hr | 1334 | 3492 | 3970 | 0.8796 | 0.8186 |
| BT-20 | Crizotinib | 10.0 | uM | LJP5 | 72 | hr | 1334 | 1070 | 3970 | 0.2695 | -0.1004 |
| BT-20 | Momelotinib | 10.0 | uM | LJP5 | 72 | hr | 1334 | 1398 | 3970 | 0.3521 | 0.0240 |
| BT-20 | Dasatinib | 10.0 | uM | LJP5 | 72 | hr | 1334 | 1091 | 3970 | 0.2749 | -0.0922 |
| BT-20 | Dasatinib | 10.0 | uM | LJP6 | 72 | hr | 1334 | 781 | 3970 | 0.1969 | -0.2098 |
| BT-20 | Dovitinib | 10.0 | uM | LJP5 | 72 | hr | 1334 | 1461 | 3970 | 0.3681 | 0.0482 |
| BT-20 | Enzastaurin | 10.0 | uM | LJP5 | 72 | hr | 1334 | 4675 | 3970 | 1.1774 | 1.2672 |
| BT-20 | Erlotinib | 10.0 | uM | LJP5 | 72 | hr | 1334 | 2541 | 3970 | 0.6401 | 0.4579 |
| BT-20 | Foretinib | 10.0 | uM | LJP5 | 72 | hr | 1334 | 820 | 3970 | 0.2067 | -0.1950 |
| BT-20 | R406 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 3284 | 3970 | 0.8270 | 0.7394 |
| BT-20 | Pictilisib | 10.0 | uM | LJP6 | 72 | hr | 1334 | 1307 | 3970 | 0.3293 | -0.0102 |
| BT-20 | Gefitinib | 10.0 | uM | LJP6 | 72 | hr | 1334 | 3574 | 3970 | 0.9001 | 0.8494 |
| BT-20 | Geldanamycin | 10.0 | uM | LJP5 | 72 | hr | 1334 | 796 | 3970 | 0.2005 | -0.2042 |
| BT-20 | Geldanamycin | 10.0 | uM | LJP6 | 72 | hr | 1334 | 679 | 3970 | 0.1712 | -0.2485 |