LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | TGX221 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5755 | 5667 | 1.0155 | 1.0205 |
| MCF7 | Torin1 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 1754 | 5667 | 0.3096 | 0.0854 |
| MCF7 | Torin2 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 1458 | 5667 | 0.2573 | 0.0162 |
| MCF7 | Tozasertib | 0.37 | uM | LJP5 | 72 | hr | 1389 | 1457 | 5667 | 0.2572 | 0.0160 |
| MCF7 | Trametinib | 0.37 | uM | LJP5 | 72 | hr | 1389 | 2689 | 5667 | 0.4745 | 0.3039 |
| MCF7 | TWS119 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5683 | 5667 | 1.0027 | 1.0035 |
| MCF7 | Vemurafenib | 0.37 | uM | LJP5 | 72 | hr | 1389 | 6152 | 5667 | 1.0854 | 1.1131 |
| MCF7 | Withaferin A | 0.37 | uM | LJP5 | 72 | hr | 1389 | 2889 | 5667 | 0.5098 | 0.3507 |
| MCF7 | Withaferin A | 0.37 | uM | LJP6 | 72 | hr | 1389 | 2590 | 5667 | 0.4570 | 0.2808 |
| MCF7 | WYE-125132 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 1854 | 5667 | 0.3272 | 0.1087 |
| MCF7 | WZ3105 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 503 | 5667 | 0.0887 | -0.2071 |
| MCF7 | XMD11-50 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 3653 | 5667 | 0.6446 | 0.5292 |
| MCF7 | Y39983 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 5306 | 5667 | 0.9362 | 0.9154 |
| MCF7 | YM 201636 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5117 | 5667 | 0.9028 | 0.8713 |
| MCF7 | ZSTK474 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 1922 | 5667 | 0.3391 | 0.1246 |
| MCF7 | Afatinib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 4646 | 5667 | 0.8198 | 0.7613 |
| MCF7 | Sigma A6730 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 3453 | 5667 | 0.6093 | 0.4825 |
| MCF7 | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 486 | 5667 | 0.0858 | -0.2110 |
| MCF7 | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 553 | 5667 | 0.0977 | -0.1952 |
| MCF7 | AZD 5438 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1223 | 5667 | 0.2158 | -0.0387 |
| MCF7 | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5388 | 5667 | 0.9507 | 0.9347 |
| MCF7 | AZD7762 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1327 | 5667 | 0.2342 | -0.0144 |
| MCF7 | AZD8055 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1511 | 5667 | 0.2666 | 0.0285 |
| MCF7 | AZD8330 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 2936 | 5667 | 0.5181 | 0.3617 |
| MCF7 | Barasertib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1814 | 5667 | 0.3201 | 0.0993 |