LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 PD0325901
0.37
uM
LJP5
 72
hr
 1389 3616 5667 0.6380 0.5205
MCF7 PD0325901
0.37
uM
LJP6
 72
hr
 1389 3098 5667 0.5466 0.3995
MCF7 PD173074
0.37
uM
LJP6
 72
hr
 1389 5549 5667 0.9791 0.9724
MCF7 PD184352
0.37
uM
LJP5
 72
hr
 1389 4444 5667 0.7841 0.7140
MCF7 Pelitinib
0.37
uM
LJP5
 72
hr
 1389 5272 5667 0.9302 0.9076
MCF7 PF431396
0.37
uM
LJP5
 72
hr
 1389 2289 5667 0.4039 0.2104
MCF7 PF477736
0.37
uM
LJP5
 72
hr
 1389 2726 5667 0.4810 0.3126
MCF7 PF562271
0.37
uM
LJP6
 72
hr
 1389 3527 5667 0.6224 0.4998
MCF7 PHA-665752
0.37
uM
LJP5
 72
hr
 1389 6395 5667 1.1284 1.1700
MCF7 PHA-793887
0.37
uM
LJP6
 72
hr
 1389 1696 5667 0.2994 0.0719
MCF7 PI103
0.37
uM
LJP6
 72
hr
 1389 1654 5667 0.2919 0.0621
MCF7 PLX-4720
0.37
uM
LJP5
 72
hr
 1389 6284 5667 1.1088 1.1441
MCF7 QL-X-138
0.37
uM
LJP6
 72
hr
 1389 2730 5667 0.4817 0.3135
MCF7 QL-XII-47
0.37
uM
LJP6
 72
hr
 1389 1728 5667 0.3050 0.0794
MCF7 Radicicol
0.37
uM
LJP5
 72
hr
 1389 1571 5667 0.2773 0.0426
MCF7 Radicicol
0.37
uM
LJP6
 72
hr
 1389 1699 5667 0.2998 0.0725
MCF7 Seliciclib
0.37
uM
LJP5
 72
hr
 1389 5718 5667 1.0089 1.0118
MCF7 Ruxolitinib
0.37
uM
LJP5
 72
hr
 1389 5681 5667 1.0023 1.0031
MCF7 XL147
0.37
uM
LJP5
 72
hr
 1389 6139 5667 1.0832 1.1102
MCF7 Saracatinib
0.37
uM
LJP6
 72
hr
 1389 2345 5667 0.4137 0.2234
MCF7 Selumetinib
0.37
uM
LJP6
 72
hr
 1389 3295 5667 0.5813 0.4454
MCF7 Sirolimus
0.37
uM
LJP6
 72
hr
 1389 3167 5667 0.5589 0.4157
MCF7 Sorafenib
0.37
uM
LJP6
 72
hr
 1389 4946 5667 0.8726 0.8313
MCF7 SU11274
0.37
uM
LJP5
 72
hr
 1389 5969 5667 1.0532 1.0705
MCF7 Fedratinib
0.37
uM
LJP5
 72
hr
 1389 5460 5667 0.9634 0.9515