LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 GSK1059615
0.37
uM
LJP5
72
hr
1389 4309 5667 0.7603 0.6824
MCF7 GSK1059615
0.37
uM
LJP6
72
hr
1389 3382 5667 0.5968 0.4658
MCF7 GSK1904529A
0.37
uM
LJP6
72
hr
1389 3076 5667 0.5427 0.3943
MCF7 Omipalisib
0.37
uM
LJP6
72
hr
1389 1294 5667 0.2283 -0.0222
MCF7 GSK 690693
0.37
uM
LJP5
72
hr
1389 3560 5667 0.6281 0.5074
MCF7 GW843682X
0.37
uM
LJP6
72
hr
1389 1883 5667 0.3322 0.1154
MCF7 HG-5-113-01
0.37
uM
LJP5
72
hr
1389 3820 5667 0.6741 0.5683
MCF7 HG-5-88-01
0.37
uM
LJP6
72
hr
1389 3381 5667 0.5965 0.4655
MCF7 Imatinib
0.37
uM
LJP6
72
hr
1389 5801 5667 1.0235 1.0312
MCF7 JNK-9L
0.37
uM
LJP6
72
hr
1389 2616 5667 0.4616 0.2868
MCF7 JW-7-24-1
0.37
uM
LJP6
72
hr
1389 3060 5667 0.5399 0.3906
MCF7 Lapatinib
0.37
uM
LJP6
72
hr
1389 5614 5667 0.9906 0.9875
MCF7 LDN-193189
0.37
uM
LJP5
72
hr
1389 5764 5667 1.0170 1.0225
MCF7 Linifanib
0.37
uM
LJP6
72
hr
1389 5056 5667 0.8921 0.8571
MCF7 Linsitinib
0.37
uM
LJP5
72
hr
1389 4606 5667 0.8127 0.7518
MCF7 Mitoxantrone
0.37
uM
LJP5
72
hr
1389 1645 5667 0.2903 0.0599
MCF7 Mitoxantrone
0.37
uM
LJP6
72
hr
1389 1295 5667 0.2286 -0.0218
MCF7 MK2206
0.37
uM
LJP6
72
hr
1389 2368 5667 0.4179 0.2289
MCF7 Neratinib
0.37
uM
LJP5
72
hr
1389 3852 5667 0.6796 0.5756
MCF7 Nilotinib
0.37
uM
LJP5
72
hr
1389 5701 5667 1.0059 1.0079
MCF7 Nintedanib
0.37
uM
LJP6
72
hr
1389 4394 5667 0.7754 0.7024
MCF7 NU7441
0.37
uM
LJP5
72
hr
1389 5519 5667 0.9738 0.9653
MCF7 Dactolisib
0.37
uM
LJP5
72
hr
1389 1790 5667 0.3159 0.0938
MCF7 NVP-TAE684
0.37
uM
LJP6
72
hr
1389 1715 5667 0.3026 0.0762
MCF7 Palbociclib
0.37
uM
LJP6
72
hr
1389 3632 5667 0.6408 0.5242