LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF7 | GSK1059615 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 4309 | 5667 | 0.7603 | 0.6824 |
MCF7 | GSK1059615 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 3382 | 5667 | 0.5968 | 0.4658 |
MCF7 | GSK1904529A | 0.37 | uM | LJP6 | 72 | hr | 1389 | 3076 | 5667 | 0.5427 | 0.3943 |
MCF7 | Omipalisib | 0.37 | uM | LJP6 | 72 | hr | 1389 | 1294 | 5667 | 0.2283 | -0.0222 |
MCF7 | GSK 690693 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 3560 | 5667 | 0.6281 | 0.5074 |
MCF7 | GW843682X | 0.37 | uM | LJP6 | 72 | hr | 1389 | 1883 | 5667 | 0.3322 | 0.1154 |
MCF7 | HG-5-113-01 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 3820 | 5667 | 0.6741 | 0.5683 |
MCF7 | HG-5-88-01 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 3381 | 5667 | 0.5965 | 0.4655 |
MCF7 | Imatinib | 0.37 | uM | LJP6 | 72 | hr | 1389 | 5801 | 5667 | 1.0235 | 1.0312 |
MCF7 | JNK-9L | 0.37 | uM | LJP6 | 72 | hr | 1389 | 2616 | 5667 | 0.4616 | 0.2868 |
MCF7 | JW-7-24-1 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 3060 | 5667 | 0.5399 | 0.3906 |
MCF7 | Lapatinib | 0.37 | uM | LJP6 | 72 | hr | 1389 | 5614 | 5667 | 0.9906 | 0.9875 |
MCF7 | LDN-193189 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5764 | 5667 | 1.0170 | 1.0225 |
MCF7 | Linifanib | 0.37 | uM | LJP6 | 72 | hr | 1389 | 5056 | 5667 | 0.8921 | 0.8571 |
MCF7 | Linsitinib | 0.37 | uM | LJP5 | 72 | hr | 1389 | 4606 | 5667 | 0.8127 | 0.7518 |
MCF7 | Mitoxantrone | 0.37 | uM | LJP5 | 72 | hr | 1389 | 1645 | 5667 | 0.2903 | 0.0599 |
MCF7 | Mitoxantrone | 0.37 | uM | LJP6 | 72 | hr | 1389 | 1295 | 5667 | 0.2286 | -0.0218 |
MCF7 | MK2206 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 2368 | 5667 | 0.4179 | 0.2289 |
MCF7 | Neratinib | 0.37 | uM | LJP5 | 72 | hr | 1389 | 3852 | 5667 | 0.6796 | 0.5756 |
MCF7 | Nilotinib | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5701 | 5667 | 1.0059 | 1.0079 |
MCF7 | Nintedanib | 0.37 | uM | LJP6 | 72 | hr | 1389 | 4394 | 5667 | 0.7754 | 0.7024 |
MCF7 | NU7441 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5519 | 5667 | 0.9738 | 0.9653 |
MCF7 | Dactolisib | 0.37 | uM | LJP5 | 72 | hr | 1389 | 1790 | 5667 | 0.3159 | 0.0938 |
MCF7 | NVP-TAE684 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 1715 | 5667 | 0.3026 | 0.0762 |
MCF7 | Palbociclib | 0.37 | uM | LJP6 | 72 | hr | 1389 | 3632 | 5667 | 0.6408 | 0.5242 |