LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 Nintedanib
3.33
uM
LJP6
 72
hr
 1389 2660 5667 0.4693 0.2970
MCF7 NU7441
3.33
uM
LJP5
 72
hr
 1389 5117 5667 0.9028 0.8713
MCF7 Dactolisib
3.33
uM
LJP5
 72
hr
 1389 1861 5667 0.3284 0.1104
MCF7 NVP-TAE684
3.33
uM
LJP6
 72
hr
 1389 1013 5667 0.1788 -0.0878
MCF7 Palbociclib
3.33
uM
LJP6
 72
hr
 1389 2633 5667 0.4646 0.2907
MCF7 PD0325901
3.33
uM
LJP5
 72
hr
 1389 2392 5667 0.4221 0.2345
MCF7 PD0325901
3.33
uM
LJP6
 72
hr
 1389 2287 5667 0.4036 0.2099
MCF7 PD173074
3.33
uM
LJP6
 72
hr
 1389 6034 5667 1.0647 1.0857
MCF7 PD184352
3.33
uM
LJP5
 72
hr
 1389 3553 5667 0.6269 0.5057
MCF7 Pelitinib
3.33
uM
LJP5
 72
hr
 1389 3172 5667 0.5597 0.4168
MCF7 PF431396
3.33
uM
LJP5
 72
hr
 1389 1405 5667 0.2479 0.0037
MCF7 PF477736
3.33
uM
LJP5
 72
hr
 1389 2002 5667 0.3532 0.1433
MCF7 PF562271
3.33
uM
LJP6
 72
hr
 1389 1233 5667 0.2177 -0.0363
MCF7 PHA-665752
3.33
uM
LJP5
 72
hr
 1389 5626 5667 0.9926 0.9902
MCF7 PHA-793887
3.33
uM
LJP6
 72
hr
 1389 1357 5667 0.2394 -0.0075
MCF7 PI103
3.33
uM
LJP6
 72
hr
 1389 1282 5667 0.2262 -0.0249
MCF7 PLX-4720
3.33
uM
LJP5
 72
hr
 1389 5426 5667 0.9573 0.9435
MCF7 QL-X-138
3.33
uM
LJP6
 72
hr
 1389 2037 5667 0.3595 0.1515
MCF7 QL-XII-47
3.33
uM
LJP6
 72
hr
 1389 1122 5667 0.1981 -0.0623
MCF7 Radicicol
3.33
uM
LJP5
 72
hr
 1389 1703 5667 0.3006 0.0735
MCF7 Radicicol
3.33
uM
LJP6
 72
hr
 1389 1609 5667 0.2839 0.0515
MCF7 Seliciclib
3.33
uM
LJP5
 72
hr
 1389 4844 5667 0.8546 0.8075
MCF7 Ruxolitinib
3.33
uM
LJP5
 72
hr
 1389 6160 5667 1.0869 1.1151
MCF7 XL147
3.33
uM
LJP5
 72
hr
 1389 6369 5667 1.1237 1.1639
MCF7 Saracatinib
3.33
uM
LJP6
 72
hr
 1389 1515 5667 0.2673 0.0294