LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 R406
3.33
uM
LJP6
 72
hr
 1389 4113 5667 0.7257 0.6366
MCF7 Pictilisib
3.33
uM
LJP6
 72
hr
 1389 1289 5667 0.2274 -0.0234
MCF7 Gefitinib
3.33
uM
LJP6
 72
hr
 1389 5503 5667 0.9710 0.9615
MCF7 Geldanamycin
3.33
uM
LJP5
 72
hr
 1389 1257 5667 0.2219 -0.0307
MCF7 Geldanamycin
3.33
uM
LJP6
 72
hr
 1389 1217 5667 0.2147 -0.0402
MCF7 GSK1059615
3.33
uM
LJP5
 72
hr
 1389 1373 5667 0.2422 -0.0038
MCF7 GSK1059615
3.33
uM
LJP6
 72
hr
 1389 1711 5667 0.3019 0.0752
MCF7 GSK1904529A
3.33
uM
LJP6
 72
hr
 1389 2829 5667 0.4991 0.3365
MCF7 Omipalisib
3.33
uM
LJP6
 72
hr
 1389 1081 5667 0.1908 -0.0718
MCF7 GSK 690693
3.33
uM
LJP5
 72
hr
 1389 2936 5667 0.5180 0.3615
MCF7 GW843682X
3.33
uM
LJP6
 72
hr
 1389 1488 5667 0.2627 0.0233
MCF7 HG-5-113-01
3.33
uM
LJP5
 72
hr
 1389 1646 5667 0.2904 0.0600
MCF7 HG-5-88-01
3.33
uM
LJP6
 72
hr
 1389 1909 5667 0.3369 0.1217
MCF7 Imatinib
3.33
uM
LJP6
 72
hr
 1389 5850 5667 1.0322 1.0427
MCF7 JNK-9L
3.33
uM
LJP6
 72
hr
 1389 957 5667 0.1690 -0.1008
MCF7 JW-7-24-1
3.33
uM
LJP6
 72
hr
 1389 2028 5667 0.3578 0.1493
MCF7 Lapatinib
3.33
uM
LJP6
 72
hr
 1389 5083 5667 0.8969 0.8634
MCF7 LDN-193189
3.33
uM
LJP5
 72
hr
 1389 3320 5667 0.5858 0.4514
MCF7 Linifanib
3.33
uM
LJP6
 72
hr
 1389 4764 5667 0.8406 0.7888
MCF7 Linsitinib
3.33
uM
LJP5
 72
hr
 1389 3143 5667 0.5545 0.4099
MCF7 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1389 626 5667 0.1105 -0.1782
MCF7 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1389 555 5667 0.0979 -0.1949
MCF7 MK2206
3.33
uM
LJP6
 72
hr
 1389 2211 5667 0.3901 0.1921
MCF7 Neratinib
3.33
uM
LJP5
 72
hr
 1389 3216 5667 0.5675 0.4271
MCF7 Nilotinib
3.33
uM
LJP5
 72
hr
 1389 5583 5667 0.9851 0.9803