LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 GW843682X
0.04
uM
LJP6
 72
hr
 1389 4561 5667 0.8048 0.7415
MCF7 HG-5-113-01
0.04
uM
LJP5
 72
hr
 1389 5118 5667 0.9030 0.8715
MCF7 HG-5-88-01
0.04
uM
LJP6
 72
hr
 1389 3675 5667 0.6485 0.5343
MCF7 Imatinib
0.04
uM
LJP6
 72
hr
 1389 5983 5667 1.0557 1.0737
MCF7 JNK-9L
0.04
uM
LJP6
 72
hr
 1389 4161 5667 0.7342 0.6479
MCF7 JW-7-24-1
0.04
uM
LJP6
 72
hr
 1389 3786 5667 0.6680 0.5602
MCF7 Lapatinib
0.04
uM
LJP6
 72
hr
 1389 4859 5667 0.8574 0.8111
MCF7 LDN-193189
0.04
uM
LJP5
 72
hr
 1389 6186 5667 1.0915 1.1212
MCF7 Linifanib
0.04
uM
LJP6
 72
hr
 1389 5459 5667 0.9633 0.9513
MCF7 Linsitinib
0.04
uM
LJP5
 72
hr
 1389 4291 5667 0.7571 0.6782
MCF7 Mitoxantrone
0.04
uM
LJP5
 72
hr
 1389 1654 5667 0.2918 0.0619
MCF7 Mitoxantrone
0.04
uM
LJP6
 72
hr
 1389 1526 5667 0.2692 0.0320
MCF7 MK2206
0.04
uM
LJP6
 72
hr
 1389 4071 5667 0.7183 0.6268
MCF7 Neratinib
0.04
uM
LJP5
 72
hr
 1389 3737 5667 0.6593 0.5487
MCF7 Nilotinib
0.04
uM
LJP5
 72
hr
 1389 6100 5667 1.0762 1.1010
MCF7 Nintedanib
0.04
uM
LJP6
 72
hr
 1389 5303 5667 0.9357 0.9148
MCF7 NU7441
0.04
uM
LJP5
 72
hr
 1389 6255 5667 1.1037 1.1373
MCF7 Dactolisib
0.04
uM
LJP5
 72
hr
 1389 2132 5667 0.3762 0.1736
MCF7 NVP-TAE684
0.04
uM
LJP6
 72
hr
 1389 4311 5667 0.7606 0.6829
MCF7 Palbociclib
0.04
uM
LJP6
 72
hr
 1389 4400 5667 0.7764 0.7038
MCF7 PD0325901
0.04
uM
LJP5
 72
hr
 1389 3848 5667 0.6789 0.5747
MCF7 PD0325901
0.04
uM
LJP6
 72
hr
 1389 3622 5667 0.6391 0.5219
MCF7 PD173074
0.04
uM
LJP6
 72
hr
 1389 6234 5667 1.0999 1.1323
MCF7 PD184352
0.04
uM
LJP5
 72
hr
 1389 6167 5667 1.0881 1.1168
MCF7 Pelitinib
0.04
uM
LJP5
 72
hr
 1389 5916 5667 1.0439 1.0581