LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD-6482 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1957 | 5667 | 0.3454 | 0.1329 |
| MCF7 | AZD7762 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 771 | 5667 | 0.1360 | -0.1445 |
| MCF7 | AZD8055 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 1120 | 5667 | 0.1977 | -0.0628 |
| MCF7 | AZD8330 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 3004 | 5667 | 0.5300 | 0.3774 |
| MCF7 | Barasertib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1663 | 5667 | 0.2935 | 0.0641 |
| MCF7 | BI-2536 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 912 | 5667 | 0.1610 | -0.1114 |
| MCF7 | BMS345541 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 421 | 5667 | 0.0743 | -0.2262 |
| MCF7 | SNS-032 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 444 | 5667 | 0.0785 | -0.2207 |
| MCF7 | GDC-0980 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1288 | 5667 | 0.2273 | -0.0235 |
| MCF7 | NVP-AEW541 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1518 | 5667 | 0.2678 | 0.0301 |
| MCF7 | SB590885 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 4408 | 5667 | 0.7777 | 0.7056 |
| MCF7 | PIK-93 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1850 | 5667 | 0.3264 | 0.1077 |
| MCF7 | KIN001-043 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 2219 | 5667 | 0.3916 | 0.1940 |
| MCF7 | Alpelisib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1460 | 5667 | 0.2577 | 0.0167 |
| MCF7 | Luminespib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1340 | 5667 | 0.2365 | -0.0113 |
| MCF7 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 547 | 5667 | 0.0966 | -0.1966 |
| MCF7 | OSI-027 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 1894 | 5667 | 0.3343 | 0.1182 |
| MCF7 | XMD11-85h | 10.0 | uM | LJP6 | 72 | hr | 1389 | 2431 | 5667 | 0.4290 | 0.2437 |
| MCF7 | HG-6-64-01 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 896 | 5667 | 0.1581 | -0.1152 |
| MCF7 | WH-4-025 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1328 | 5667 | 0.2344 | -0.0142 |
| MCF7 | WZ-4-145 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 579 | 5667 | 0.1022 | -0.1892 |
| MCF7 | XMD16-144 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 721 | 5667 | 0.1273 | -0.1560 |
| MCF7 | Brivanib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 5061 | 5667 | 0.8930 | 0.8583 |
| MCF7 | Buparlisib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 844 | 5667 | 0.1489 | -0.1274 |
| MCF7 | BX-912 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1535 | 5667 | 0.2709 | 0.0342 |