LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 WZ-4-145
0.12
uM
LJP6
 72
hr
 1311 4569 5013 0.9113 0.8799
MDA-MB-231 XMD16-144
0.12
uM
LJP5
 72
hr
 1311 1577 5013 0.3146 0.0718
MDA-MB-231 Brivanib
0.12
uM
LJP5
 72
hr
 1311 4947 5013 0.9868 0.9821
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 72
hr
 1311 4960 5013 0.9895 0.9857
MDA-MB-231 BX-912
0.12
uM
LJP5
 72
hr
 1311 4923 5013 0.9821 0.9757
MDA-MB-231 Canertinib
0.12
uM
LJP6
 72
hr
 1311 4785 5013 0.9545 0.9384
MDA-MB-231 Celastrol
0.12
uM
LJP6
 72
hr
 1311 4980 5013 0.9934 0.9910
MDA-MB-231 CGP60474
0.12
uM
LJP5
 72
hr
 1311 1271 5013 0.2537 -0.0108
MDA-MB-231 CGP60474
0.12
uM
LJP6
 72
hr
 1311 791 5013 0.1578 -0.1406
MDA-MB-231 CHIR-99021
0.12
uM
LJP6
 72
hr
 1311 4267 5013 0.8512 0.7985
MDA-MB-231 CP724714
0.12
uM
LJP5
 72
hr
 1311 4723 5013 0.9421 0.9216
MDA-MB-231 CP466722
0.12
uM
LJP5
 72
hr
 1311 5059 5013 1.0091 1.0124
MDA-MB-231 Crizotinib
0.12
uM
LJP5
 72
hr
 1311 4560 5013 0.9095 0.8775
MDA-MB-231 Momelotinib
0.12
uM
LJP5
 72
hr
 1311 4298 5013 0.8574 0.8069
MDA-MB-231 Dasatinib
0.12
uM
LJP5
 72
hr
 1311 1229 5013 0.2451 -0.0223
MDA-MB-231 Dasatinib
0.12
uM
LJP6
 72
hr
 1311 899 5013 0.1793 -0.1115
MDA-MB-231 Dovitinib
0.12
uM
LJP5
 72
hr
 1311 4826 5013 0.9627 0.9494
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 72
hr
 1311 4986 5013 0.9945 0.9926
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 72
hr
 1311 4941 5013 0.9857 0.9806
MDA-MB-231 Foretinib
0.12
uM
LJP5
 72
hr
 1311 3313 5013 0.6608 0.5406
MDA-MB-231 R406
0.12
uM
LJP6
 72
hr
 1311 4919 5013 0.9813 0.9747
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 72
hr
 1311 4253 5013 0.8484 0.7947
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 72
hr
 1311 5020 5013 1.0014 1.0018
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 72
hr
 1311 1743 5013 0.3478 0.1167
MDA-MB-231 Geldanamycin
0.12
uM
LJP6
 72
hr
 1311 1521 5013 0.3034 0.0565