LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Afatinib
0.12
uM
LJP6
 72
hr
 1311 4369 5013 0.8714 0.8259
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 72
hr
 1311 4674 5013 0.9323 0.9084
MDA-MB-231 Alvocidib
0.12
uM
LJP6
 72
hr
 1311 866 5013 0.1727 -0.1204
MDA-MB-231 AT-7519
0.12
uM
LJP6
 72
hr
 1311 2609 5013 0.5205 0.3505
MDA-MB-231 AZD 5438
0.12
uM
LJP6
 72
hr
 1311 3406 5013 0.6794 0.5658
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 72
hr
 1311 4556 5013 0.9087 0.8764
MDA-MB-231 AZD7762
0.12
uM
LJP6
 72
hr
 1311 2858 5013 0.5701 0.4178
MDA-MB-231 AZD8055
0.12
uM
LJP6
 72
hr
 1311 2249 5013 0.4487 0.2533
MDA-MB-231 AZD8330
0.12
uM
LJP5
 72
hr
 1311 1566 5013 0.3124 0.0688
MDA-MB-231 Barasertib
0.12
uM
LJP5
 72
hr
 1311 1628 5013 0.3248 0.0855
MDA-MB-231 BI-2536
0.12
uM
LJP6
 72
hr
 1311 1278 5013 0.2550 -0.0089
MDA-MB-231 BMS345541
0.12
uM
LJP6
 72
hr
 1311 4651 5013 0.9278 0.9022
MDA-MB-231 SNS-032
0.12
uM
LJP6
 72
hr
 1311 813 5013 0.1622 -0.1347
MDA-MB-231 GDC-0980
0.12
uM
LJP5
 72
hr
 1311 3669 5013 0.7320 0.6370
MDA-MB-231 NVP-AEW541
0.12
uM
LJP5
 72
hr
 1311 4824 5013 0.9622 0.9488
MDA-MB-231 SB590885
0.12
uM
LJP5
 72
hr
 1311 5295 5013 1.0561 1.0760
MDA-MB-231 PIK-93
0.12
uM
LJP5
 72
hr
 1311 5226 5013 1.0425 1.0576
MDA-MB-231 KIN001-043
0.12
uM
LJP6
 72
hr
 1311 4255 5013 0.8488 0.7953
MDA-MB-231 Alpelisib
0.12
uM
LJP5
 72
hr
 1311 5184 5013 1.0340 1.0461
MDA-MB-231 Luminespib
0.12
uM
LJP5
 72
hr
 1311 993 5013 0.1982 -0.0859
MDA-MB-231 A443654
0.12
uM
LJP6
 72
hr
 1311 3262 5013 0.6506 0.5269
MDA-MB-231 OSI-027
0.12
uM
LJP6
 72
hr
 1311 4501 5013 0.8978 0.8616
MDA-MB-231 XMD11-85h
0.12
uM
LJP6
 72
hr
 1311 4668 5013 0.9311 0.9067
MDA-MB-231 HG-6-64-01
0.12
uM
LJP6
 72
hr
 1311 4753 5013 0.9481 0.9297
MDA-MB-231 WH-4-025
0.12
uM
LJP5
 72
hr
 1311 3246 5013 0.6475 0.5226