LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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MDA-MB-231 | GSK1059615 | 0.12 | uM | LJP5 | 72 | hr | 1311 | 4965 | 5013 | 0.9903 | 0.9869 |
MDA-MB-231 | GSK1059615 | 0.12 | uM | LJP6 | 72 | hr | 1311 | 4874 | 5013 | 0.9722 | 0.9624 |
MDA-MB-231 | GSK1904529A | 0.12 | uM | LJP6 | 72 | hr | 1311 | 4447 | 5013 | 0.8871 | 0.8471 |
MDA-MB-231 | Omipalisib | 0.12 | uM | LJP6 | 72 | hr | 1311 | 2232 | 5013 | 0.4452 | 0.2486 |
MDA-MB-231 | GSK 690693 | 0.12 | uM | LJP5 | 72 | hr | 1311 | 4722 | 5013 | 0.9419 | 0.9213 |
MDA-MB-231 | GW843682X | 0.12 | uM | LJP6 | 72 | hr | 1311 | 4279 | 5013 | 0.8536 | 0.8018 |
MDA-MB-231 | HG-5-113-01 | 0.12 | uM | LJP5 | 72 | hr | 1311 | 4523 | 5013 | 0.9022 | 0.8675 |
MDA-MB-231 | HG-5-88-01 | 0.12 | uM | LJP6 | 72 | hr | 1311 | 4430 | 5013 | 0.8836 | 0.8424 |
MDA-MB-231 | Imatinib | 0.12 | uM | LJP6 | 72 | hr | 1311 | 4843 | 5013 | 0.9661 | 0.9541 |
MDA-MB-231 | JNK-9L | 0.12 | uM | LJP6 | 72 | hr | 1311 | 3804 | 5013 | 0.7588 | 0.6733 |
MDA-MB-231 | JW-7-24-1 | 0.12 | uM | LJP6 | 72 | hr | 1311 | 4468 | 5013 | 0.8913 | 0.8527 |
MDA-MB-231 | Lapatinib | 0.12 | uM | LJP6 | 72 | hr | 1311 | 4692 | 5013 | 0.9360 | 0.9133 |
MDA-MB-231 | LDN-193189 | 0.12 | uM | LJP5 | 72 | hr | 1311 | 4576 | 5013 | 0.9127 | 0.8818 |
MDA-MB-231 | Linifanib | 0.12 | uM | LJP6 | 72 | hr | 1311 | 5238 | 5013 | 1.0448 | 1.0606 |
MDA-MB-231 | Linsitinib | 0.12 | uM | LJP5 | 72 | hr | 1311 | 4687 | 5013 | 0.9349 | 0.9118 |
MDA-MB-231 | Mitoxantrone | 0.12 | uM | LJP5 | 72 | hr | 1311 | 1198 | 5013 | 0.2390 | -0.0307 |
MDA-MB-231 | Mitoxantrone | 0.12 | uM | LJP6 | 72 | hr | 1311 | 1073 | 5013 | 0.2140 | -0.0645 |
MDA-MB-231 | MK2206 | 0.12 | uM | LJP6 | 72 | hr | 1311 | 4681 | 5013 | 0.9338 | 0.9104 |
MDA-MB-231 | Neratinib | 0.12 | uM | LJP5 | 72 | hr | 1311 | 4784 | 5013 | 0.9543 | 0.9381 |
MDA-MB-231 | Nilotinib | 0.12 | uM | LJP5 | 72 | hr | 1311 | 5066 | 5013 | 1.0105 | 1.0143 |
MDA-MB-231 | Nintedanib | 0.12 | uM | LJP6 | 72 | hr | 1311 | 5131 | 5013 | 1.0236 | 1.0319 |
MDA-MB-231 | NU7441 | 0.12 | uM | LJP5 | 72 | hr | 1311 | 4629 | 5013 | 0.9234 | 0.8962 |
MDA-MB-231 | Dactolisib | 0.12 | uM | LJP5 | 72 | hr | 1311 | 2402 | 5013 | 0.4791 | 0.2945 |
MDA-MB-231 | NVP-TAE684 | 0.12 | uM | LJP6 | 72 | hr | 1311 | 4110 | 5013 | 0.8199 | 0.7561 |
MDA-MB-231 | Palbociclib | 0.12 | uM | LJP6 | 72 | hr | 1311 | 3289 | 5013 | 0.6562 | 0.5343 |