LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 GSK1059615
0.12
uM
LJP5
72
hr
1311 4965 5013 0.9903 0.9869
MDA-MB-231 GSK1059615
0.12
uM
LJP6
72
hr
1311 4874 5013 0.9722 0.9624
MDA-MB-231 GSK1904529A
0.12
uM
LJP6
72
hr
1311 4447 5013 0.8871 0.8471
MDA-MB-231 Omipalisib
0.12
uM
LJP6
72
hr
1311 2232 5013 0.4452 0.2486
MDA-MB-231 GSK 690693
0.12
uM
LJP5
72
hr
1311 4722 5013 0.9419 0.9213
MDA-MB-231 GW843682X
0.12
uM
LJP6
72
hr
1311 4279 5013 0.8536 0.8018
MDA-MB-231 HG-5-113-01
0.12
uM
LJP5
72
hr
1311 4523 5013 0.9022 0.8675
MDA-MB-231 HG-5-88-01
0.12
uM
LJP6
72
hr
1311 4430 5013 0.8836 0.8424
MDA-MB-231 Imatinib
0.12
uM
LJP6
72
hr
1311 4843 5013 0.9661 0.9541
MDA-MB-231 JNK-9L
0.12
uM
LJP6
72
hr
1311 3804 5013 0.7588 0.6733
MDA-MB-231 JW-7-24-1
0.12
uM
LJP6
72
hr
1311 4468 5013 0.8913 0.8527
MDA-MB-231 Lapatinib
0.12
uM
LJP6
72
hr
1311 4692 5013 0.9360 0.9133
MDA-MB-231 LDN-193189
0.12
uM
LJP5
72
hr
1311 4576 5013 0.9127 0.8818
MDA-MB-231 Linifanib
0.12
uM
LJP6
72
hr
1311 5238 5013 1.0448 1.0606
MDA-MB-231 Linsitinib
0.12
uM
LJP5
72
hr
1311 4687 5013 0.9349 0.9118
MDA-MB-231 Mitoxantrone
0.12
uM
LJP5
72
hr
1311 1198 5013 0.2390 -0.0307
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
72
hr
1311 1073 5013 0.2140 -0.0645
MDA-MB-231 MK2206
0.12
uM
LJP6
72
hr
1311 4681 5013 0.9338 0.9104
MDA-MB-231 Neratinib
0.12
uM
LJP5
72
hr
1311 4784 5013 0.9543 0.9381
MDA-MB-231 Nilotinib
0.12
uM
LJP5
72
hr
1311 5066 5013 1.0105 1.0143
MDA-MB-231 Nintedanib
0.12
uM
LJP6
72
hr
1311 5131 5013 1.0236 1.0319
MDA-MB-231 NU7441
0.12
uM
LJP5
72
hr
1311 4629 5013 0.9234 0.8962
MDA-MB-231 Dactolisib
0.12
uM
LJP5
72
hr
1311 2402 5013 0.4791 0.2945
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
72
hr
1311 4110 5013 0.8199 0.7561
MDA-MB-231 Palbociclib
0.12
uM
LJP6
72
hr
1311 3289 5013 0.6562 0.5343