LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 PD0325901
0.12
uM
LJP5
 72
hr
 1311 2543 5013 0.5072 0.3326
MDA-MB-231 PD0325901
0.12
uM
LJP6
 72
hr
 1311 2371 5013 0.4729 0.2862
MDA-MB-231 PD173074
0.12
uM
LJP6
 72
hr
 1311 5103 5013 1.0178 1.0242
MDA-MB-231 PD184352
0.12
uM
LJP5
 72
hr
 1311 4341 5013 0.8660 0.8185
MDA-MB-231 Pelitinib
0.12
uM
LJP5
 72
hr
 1311 5253 5013 1.0479 1.0649
MDA-MB-231 PF431396
0.12
uM
LJP5
 72
hr
 1311 4067 5013 0.8112 0.7443
MDA-MB-231 PF477736
0.12
uM
LJP5
 72
hr
 1311 5116 5013 1.0205 1.0278
MDA-MB-231 PF562271
0.12
uM
LJP6
 72
hr
 1311 4387 5013 0.8751 0.8308
MDA-MB-231 PHA-665752
0.12
uM
LJP5
 72
hr
 1311 4933 5013 0.9840 0.9783
MDA-MB-231 PHA-793887
0.12
uM
LJP6
 72
hr
 1311 2138 5013 0.4265 0.2233
MDA-MB-231 PI103
0.12
uM
LJP6
 72
hr
 1311 3706 5013 0.7393 0.6469
MDA-MB-231 PLX-4720
0.12
uM
LJP5
 72
hr
 1311 5140 5013 1.0252 1.0342
MDA-MB-231 QL-X-138
0.12
uM
LJP6
 72
hr
 1311 4378 5013 0.8732 0.8283
MDA-MB-231 QL-XII-47
0.12
uM
LJP6
 72
hr
 1311 3558 5013 0.7097 0.6068
MDA-MB-231 Radicicol
0.12
uM
LJP5
 72
hr
 1311 4268 5013 0.8513 0.7986
MDA-MB-231 Radicicol
0.12
uM
LJP6
 72
hr
 1311 4328 5013 0.8633 0.8148
MDA-MB-231 Seliciclib
0.12
uM
LJP5
 72
hr
 1311 5018 5013 1.0009 1.0012
MDA-MB-231 Ruxolitinib
0.12
uM
LJP5
 72
hr
 1311 4994 5013 0.9961 0.9947
MDA-MB-231 XL147
0.12
uM
LJP5
 72
hr
 1311 4825 5013 0.9625 0.9492
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 72
hr
 1311 3312 5013 0.6606 0.5404
MDA-MB-231 Selumetinib
0.12
uM
LJP6
 72
hr
 1311 3266 5013 0.6514 0.5279
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 72
hr
 1311 4149 5013 0.8276 0.7666
MDA-MB-231 Sorafenib
0.12
uM
LJP6
 72
hr
 1311 4641 5013 0.9258 0.8995
MDA-MB-231 SU11274
0.12
uM
LJP5
 72
hr
 1311 5214 5013 1.0401 1.0543
MDA-MB-231 Fedratinib
0.12
uM
LJP5
 72
hr
 1311 4858 5013 0.9690 0.9580