LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Nintedanib
1.11
uM
LJP6
 72
hr
 1311 4771 5013 0.9518 0.9347
MDA-MB-231 NU7441
1.11
uM
LJP5
 72
hr
 1311 4461 5013 0.8898 0.8507
MDA-MB-231 Dactolisib
1.11
uM
LJP5
 72
hr
 1311 2084 5013 0.4157 0.2086
MDA-MB-231 NVP-TAE684
1.11
uM
LJP6
 72
hr
 1311 2840 5013 0.5665 0.4129
MDA-MB-231 Palbociclib
1.11
uM
LJP6
 72
hr
 1311 2692 5013 0.5370 0.3729
MDA-MB-231 PD0325901
1.11
uM
LJP5
 72
hr
 1311 1708 5013 0.3407 0.1071
MDA-MB-231 PD0325901
1.11
uM
LJP6
 72
hr
 1311 1604 5013 0.3199 0.0790
MDA-MB-231 PD173074
1.11
uM
LJP6
 72
hr
 1311 5190 5013 1.0352 1.0477
MDA-MB-231 PD184352
1.11
uM
LJP5
 72
hr
 1311 3403 5013 0.6788 0.5650
MDA-MB-231 Pelitinib
1.11
uM
LJP5
 72
hr
 1311 4330 5013 0.8638 0.8155
MDA-MB-231 PF431396
1.11
uM
LJP5
 72
hr
 1311 1938 5013 0.3866 0.1692
MDA-MB-231 PF477736
1.11
uM
LJP5
 72
hr
 1311 3969 5013 0.7917 0.7178
MDA-MB-231 PF562271
1.11
uM
LJP6
 72
hr
 1311 3483 5013 0.6947 0.5866
MDA-MB-231 PHA-665752
1.11
uM
LJP5
 72
hr
 1311 4801 5013 0.9577 0.9427
MDA-MB-231 PHA-793887
1.11
uM
LJP6
 72
hr
 1311 1265 5013 0.2525 -0.0124
MDA-MB-231 PI103
1.11
uM
LJP6
 72
hr
 1311 2447 5013 0.4882 0.3069
MDA-MB-231 PLX-4720
1.11
uM
LJP5
 72
hr
 1311 4897 5013 0.9768 0.9685
MDA-MB-231 QL-X-138
1.11
uM
LJP6
 72
hr
 1311 3975 5013 0.7929 0.7195
MDA-MB-231 QL-XII-47
1.11
uM
LJP6
 72
hr
 1311 2028 5013 0.4046 0.1936
MDA-MB-231 Radicicol
1.11
uM
LJP5
 72
hr
 1311 1593 5013 0.3178 0.0761
MDA-MB-231 Radicicol
1.11
uM
LJP6
 72
hr
 1311 1606 5013 0.3205 0.0797
MDA-MB-231 Seliciclib
1.11
uM
LJP5
 72
hr
 1311 4676 5013 0.9327 0.9089
MDA-MB-231 Ruxolitinib
1.11
uM
LJP5
 72
hr
 1311 5099 5013 1.0172 1.0233
MDA-MB-231 XL147
1.11
uM
LJP5
 72
hr
 1311 5004 5013 0.9981 0.9974
MDA-MB-231 Saracatinib
1.11
uM
LJP6
 72
hr
 1311 2524 5013 0.5034 0.3275