LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Radicicol
10.0
uM
LJP6
 72
hr
 1311 1256 5013 0.2506 -0.0150
MDA-MB-231 Seliciclib
10.0
uM
LJP5
 72
hr
 1311 2705 5013 0.5396 0.3765
MDA-MB-231 Ruxolitinib
10.0
uM
LJP5
 72
hr
 1311 4378 5013 0.8733 0.8284
MDA-MB-231 XL147
10.0
uM
LJP5
 72
hr
 1311 4400 5013 0.8778 0.8344
MDA-MB-231 Saracatinib
10.0
uM
LJP6
 72
hr
 1311 2008 5013 0.4006 0.1882
MDA-MB-231 Selumetinib
10.0
uM
LJP6
 72
hr
 1311 1752 5013 0.3495 0.1189
MDA-MB-231 Sirolimus
10.0
uM
LJP6
 72
hr
 1311 4299 5013 0.8575 0.8070
MDA-MB-231 Sorafenib
10.0
uM
LJP6
 72
hr
 1311 4434 5013 0.8845 0.8435
MDA-MB-231 SU11274
10.0
uM
LJP5
 72
hr
 1311 1655 5013 0.3302 0.0929
MDA-MB-231 Fedratinib
10.0
uM
LJP5
 72
hr
 1311 642 5013 0.1281 -0.1809
MDA-MB-231 TGX221
10.0
uM
LJP5
 72
hr
 1311 4596 5013 0.9168 0.8873
MDA-MB-231 Torin1
10.0
uM
LJP6
 72
hr
 1311 1164 5013 0.2323 -0.0397
MDA-MB-231 Torin2
10.0
uM
LJP5
 72
hr
 1311 780 5013 0.1557 -0.1435
MDA-MB-231 Tozasertib
10.0
uM
LJP5
 72
hr
 1311 1419 5013 0.2830 0.0290
MDA-MB-231 Trametinib
10.0
uM
LJP5
 72
hr
 1311 1683 5013 0.3358 0.1004
MDA-MB-231 TWS119
10.0
uM
LJP5
 72
hr
 1311 1542 5013 0.3076 0.0623
MDA-MB-231 Vemurafenib
10.0
uM
LJP5
 72
hr
 1311 2744 5013 0.5474 0.3870
MDA-MB-231 Withaferin A
10.0
uM
LJP5
 72
hr
 1311 466 5013 0.0929 -0.2285
MDA-MB-231 Withaferin A
10.0
uM
LJP6
 72
hr
 1311 379 5013 0.0757 -0.2519
MDA-MB-231 WYE-125132
10.0
uM
LJP6
 72
hr
 1311 1436 5013 0.2865 0.0337
MDA-MB-231 WZ3105
10.0
uM
LJP5
 72
hr
 1311 1027 5013 0.2049 -0.0769
MDA-MB-231 XMD11-50
10.0
uM
LJP6
 72
hr
 1311 1367 5013 0.2728 0.0151
MDA-MB-231 Y39983
10.0
uM
LJP6
 72
hr
 1311 724 5013 0.1445 -0.1586
MDA-MB-231 YM 201636
10.0
uM
LJP5
 72
hr
 1311 1386 5013 0.2765 0.0202
MDA-MB-231 ZSTK474
10.0
uM
LJP6
 72
hr
 1311 2522 5013 0.5032 0.3271