LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Afatinib | 0.04 | uM | LJP6 | 72 | hr | 2543 | 1536 | 5578 | 0.2754 | -0.3318 |
| SK-BR-3 | Sigma A6730 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 4404 | 5578 | 0.7896 | 0.6132 |
| SK-BR-3 | Alvocidib | 0.04 | uM | LJP6 | 72 | hr | 2543 | 2952 | 5578 | 0.5293 | 0.1348 |
| SK-BR-3 | AT-7519 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 5140 | 5578 | 0.9214 | 0.8556 |
| SK-BR-3 | AZD 5438 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 5060 | 5578 | 0.9072 | 0.8293 |
| SK-BR-3 | AZD-6482 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5673 | 5578 | 1.0170 | 1.0312 |
| SK-BR-3 | AZD7762 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 2030 | 5578 | 0.3639 | -0.1692 |
| SK-BR-3 | AZD8055 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 2013 | 5578 | 0.3608 | -0.1748 |
| SK-BR-3 | AZD8330 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 3814 | 5578 | 0.6838 | 0.4188 |
| SK-BR-3 | Barasertib | 0.04 | uM | LJP5 | 72 | hr | 2543 | 2155 | 5578 | 0.3864 | -0.1278 |
| SK-BR-3 | BI-2536 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 1493 | 5578 | 0.2677 | -0.3460 |
| SK-BR-3 | BMS345541 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 5441 | 5578 | 0.9754 | 0.9549 |
| SK-BR-3 | SNS-032 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 4001 | 5578 | 0.7173 | 0.4804 |
| SK-BR-3 | GDC-0980 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 3273 | 5578 | 0.5867 | 0.2404 |
| SK-BR-3 | NVP-AEW541 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5921 | 5578 | 1.0615 | 1.1130 |
| SK-BR-3 | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 6271 | 5578 | 1.1242 | 1.2283 |
| SK-BR-3 | PIK-93 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 6046 | 5578 | 1.0839 | 1.1542 |
| SK-BR-3 | KIN001-043 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 5261 | 5578 | 0.9431 | 0.8953 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5299 | 5578 | 0.9500 | 0.9081 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 72 | hr | 2543 | 2141 | 5578 | 0.3838 | -0.1326 |
| SK-BR-3 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 1613 | 5578 | 0.2892 | -0.3065 |
| SK-BR-3 | OSI-027 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 4867 | 5578 | 0.8725 | 0.7656 |
| SK-BR-3 | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 2543 | 4045 | 5578 | 0.7251 | 0.4947 |
| SK-BR-3 | HG-6-64-01 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 6137 | 5578 | 1.1002 | 1.1842 |
| SK-BR-3 | WH-4-025 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 6253 | 5578 | 1.1209 | 1.2222 |