LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Selumetinib
1.11
uM
LJP6
 72
hr
 1311 2510 5013 0.5007 0.3238
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 72
hr
 1311 4180 5013 0.8339 0.7750
MDA-MB-231 Sorafenib
1.11
uM
LJP6
 72
hr
 1311 5080 5013 1.0134 1.0181
MDA-MB-231 SU11274
1.11
uM
LJP5
 72
hr
 1311 4987 5013 0.9947 0.9928
MDA-MB-231 Fedratinib
1.11
uM
LJP5
 72
hr
 1311 4327 5013 0.8632 0.8147
MDA-MB-231 TGX221
1.11
uM
LJP5
 72
hr
 1311 4311 5013 0.8599 0.8103
MDA-MB-231 Torin1
1.11
uM
LJP6
 72
hr
 1311 1790 5013 0.3572 0.1294
MDA-MB-231 Torin2
1.11
uM
LJP5
 72
hr
 1311 1600 5013 0.3192 0.0780
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 72
hr
 1311 1440 5013 0.2874 0.0348
MDA-MB-231 Trametinib
1.11
uM
LJP5
 72
hr
 1311 1731 5013 0.3453 0.1133
MDA-MB-231 TWS119
1.11
uM
LJP5
 72
hr
 1311 3957 5013 0.7893 0.7147
MDA-MB-231 Vemurafenib
1.11
uM
LJP5
 72
hr
 1311 4731 5013 0.9438 0.9239
MDA-MB-231 Withaferin A
1.11
uM
LJP5
 72
hr
 1311 1384 5013 0.2762 0.0197
MDA-MB-231 Withaferin A
1.11
uM
LJP6
 72
hr
 1311 1295 5013 0.2584 -0.0043
MDA-MB-231 WYE-125132
1.11
uM
LJP6
 72
hr
 1311 1996 5013 0.3983 0.1850
MDA-MB-231 WZ3105
1.11
uM
LJP5
 72
hr
 1311 832 5013 0.1660 -0.1296
MDA-MB-231 XMD11-50
1.11
uM
LJP6
 72
hr
 1311 2613 5013 0.5213 0.3517
MDA-MB-231 Y39983
1.11
uM
LJP6
 72
hr
 1311 4006 5013 0.7991 0.7279
MDA-MB-231 YM 201636
1.11
uM
LJP5
 72
hr
 1311 4030 5013 0.8039 0.7344
MDA-MB-231 ZSTK474
1.11
uM
LJP6
 72
hr
 1311 3595 5013 0.7171 0.6169
MDA-MB-231 Afatinib
3.33
uM
LJP6
 72
hr
 1311 2811 5013 0.5608 0.4052
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 72
hr
 1311 4571 5013 0.9118 0.8806
MDA-MB-231 Alvocidib
3.33
uM
LJP6
 72
hr
 1311 734 5013 0.1465 -0.1560
MDA-MB-231 AT-7519
3.33
uM
LJP6
 72
hr
 1311 613 5013 0.1223 -0.1888
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 72
hr
 1311 771 5013 0.1538 -0.1461