LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 AZD-6482
3.33
uM
LJP5
 72
hr
 1311 3845 5013 0.7670 0.6844
MDA-MB-231 AZD7762
3.33
uM
LJP6
 72
hr
 1311 785 5013 0.1567 -0.1421
MDA-MB-231 AZD8055
3.33
uM
LJP6
 72
hr
 1311 1873 5013 0.3737 0.1517
MDA-MB-231 AZD8330
3.33
uM
LJP5
 72
hr
 1311 1657 5013 0.3306 0.0934
MDA-MB-231 Barasertib
3.33
uM
LJP5
 72
hr
 1311 1607 5013 0.3207 0.0799
MDA-MB-231 BI-2536
3.33
uM
LJP6
 72
hr
 1311 1296 5013 0.2586 -0.0042
MDA-MB-231 BMS345541
3.33
uM
LJP6
 72
hr
 1311 2458 5013 0.4903 0.3097
MDA-MB-231 SNS-032
3.33
uM
LJP6
 72
hr
 1311 804 5013 0.1604 -0.1371
MDA-MB-231 GDC-0980
3.33
uM
LJP5
 72
hr
 1311 2148 5013 0.4285 0.2260
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
 72
hr
 1311 4780 5013 0.9535 0.9370
MDA-MB-231 SB590885
3.33
uM
LJP5
 72
hr
 1311 4293 5013 0.8564 0.8055
MDA-MB-231 PIK-93
3.33
uM
LJP5
 72
hr
 1311 4073 5013 0.8125 0.7461
MDA-MB-231 KIN001-043
3.33
uM
LJP6
 72
hr
 1311 4481 5013 0.8938 0.8561
MDA-MB-231 Alpelisib
3.33
uM
LJP5
 72
hr
 1311 4556 5013 0.9089 0.8766
MDA-MB-231 Luminespib
3.33
uM
LJP5
 72
hr
 1311 1051 5013 0.2096 -0.0704
MDA-MB-231 A443654
3.33
uM
LJP6
 72
hr
 1311 1131 5013 0.2257 -0.0486
MDA-MB-231 OSI-027
3.33
uM
LJP6
 72
hr
 1311 3146 5013 0.6276 0.4956
MDA-MB-231 XMD11-85h
3.33
uM
LJP6
 72
hr
 1311 4256 5013 0.8489 0.7954
MDA-MB-231 HG-6-64-01
3.33
uM
LJP6
 72
hr
 1311 1901 5013 0.3792 0.1593
MDA-MB-231 WH-4-025
3.33
uM
LJP5
 72
hr
 1311 1492 5013 0.2976 0.0487
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 72
hr
 1311 4029 5013 0.8036 0.7340
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 72
hr
 1311 1531 5013 0.3055 0.0594
MDA-MB-231 Brivanib
3.33
uM
LJP5
 72
hr
 1311 5080 5013 1.0133 1.0180
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 72
hr
 1311 1607 5013 0.3205 0.0798
MDA-MB-231 BX-912
3.33
uM
LJP5
 72
hr
 1311 2012 5013 0.4014 0.1893