LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Canertinib
3.33
uM
LJP6
 72
hr
 1311 3399 5013 0.6780 0.5639
MDA-MB-231 Celastrol
3.33
uM
LJP6
 72
hr
 1311 1207 5013 0.2409 -0.0281
MDA-MB-231 CGP60474
3.33
uM
LJP5
 72
hr
 1311 759 5013 0.1514 -0.1493
MDA-MB-231 CGP60474
3.33
uM
LJP6
 72
hr
 1311 606 5013 0.1210 -0.1905
MDA-MB-231 CHIR-99021
3.33
uM
LJP6
 72
hr
 1311 4289 5013 0.8556 0.8045
MDA-MB-231 CP724714
3.33
uM
LJP5
 72
hr
 1311 4638 5013 0.9252 0.8987
MDA-MB-231 CP466722
3.33
uM
LJP5
 72
hr
 1311 4685 5013 0.9345 0.9113
MDA-MB-231 Crizotinib
3.33
uM
LJP5
 72
hr
 1311 2206 5013 0.4400 0.2416
MDA-MB-231 Momelotinib
3.33
uM
LJP5
 72
hr
 1311 2876 5013 0.5737 0.4226
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 72
hr
 1311 956 5013 0.1908 -0.0959
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 72
hr
 1311 874 5013 0.1745 -0.1181
MDA-MB-231 Dovitinib
3.33
uM
LJP5
 72
hr
 1311 2456 5013 0.4900 0.3093
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 72
hr
 1311 4917 5013 0.9808 0.9739
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 72
hr
 1311 4951 5013 0.9876 0.9832
MDA-MB-231 Foretinib
3.33
uM
LJP5
 72
hr
 1311 1321 5013 0.2636 0.0027
MDA-MB-231 R406
3.33
uM
LJP6
 72
hr
 1311 3261 5013 0.6504 0.5266
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 72
hr
 1311 3377 5013 0.6736 0.5579
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 72
hr
 1311 4967 5013 0.9907 0.9874
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 72
hr
 1311 928 5013 0.1852 -0.1036
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 72
hr
 1311 874 5013 0.1743 -0.1182
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 72
hr
 1311 1914 5013 0.3818 0.1627
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 72
hr
 1311 3119 5013 0.6222 0.4883
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 72
hr
 1311 4775 5013 0.9524 0.9356
MDA-MB-231 Omipalisib
3.33
uM
LJP6
 72
hr
 1311 888 5013 0.1771 -0.1145
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 72
hr
 1311 4949 5013 0.9872 0.9827