LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 TGX221
0.12
uM
LJP5
 72
hr
 1311 4386 5013 0.8748 0.8305
MDA-MB-231 Torin1
0.12
uM
LJP6
 72
hr
 1311 2243 5013 0.4475 0.2518
MDA-MB-231 Torin2
0.12
uM
LJP5
 72
hr
 1311 1968 5013 0.3926 0.1774
MDA-MB-231 Tozasertib
0.12
uM
LJP5
 72
hr
 1311 1381 5013 0.2756 0.0189
MDA-MB-231 Trametinib
0.12
uM
LJP5
 72
hr
 1311 1739 5013 0.3470 0.1156
MDA-MB-231 TWS119
0.12
uM
LJP5
 72
hr
 1311 4878 5013 0.9730 0.9634
MDA-MB-231 Vemurafenib
0.12
uM
LJP5
 72
hr
 1311 4839 5013 0.9653 0.9529
MDA-MB-231 Withaferin A
0.12
uM
LJP5
 72
hr
 1311 4805 5013 0.9584 0.9437
MDA-MB-231 Withaferin A
0.12
uM
LJP6
 72
hr
 1311 4866 5013 0.9707 0.9603
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 72
hr
 1311 2463 5013 0.4913 0.3110
MDA-MB-231 WZ3105
0.12
uM
LJP5
 72
hr
 1311 831 5013 0.1658 -0.1298
MDA-MB-231 XMD11-50
0.12
uM
LJP6
 72
hr
 1311 4526 5013 0.9028 0.8683
MDA-MB-231 Y39983
0.12
uM
LJP6
 72
hr
 1311 4676 5013 0.9327 0.9088
MDA-MB-231 YM 201636
0.12
uM
LJP5
 72
hr
 1311 5101 5013 1.0175 1.0237
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 72
hr
 1311 4180 5013 0.8337 0.7748
MDA-MB-231 Afatinib
0.37
uM
LJP6
 72
hr
 1311 3658 5013 0.7296 0.6338
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 72
hr
 1311 4755 5013 0.9484 0.9302
MDA-MB-231 Alvocidib
0.37
uM
LJP6
 72
hr
 1311 761 5013 0.1518 -0.1488
MDA-MB-231 AT-7519
0.37
uM
LJP6
 72
hr
 1311 913 5013 0.1822 -0.1075
MDA-MB-231 AZD 5438
0.37
uM
LJP6
 72
hr
 1311 2254 5013 0.4497 0.2547
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 72
hr
 1311 4495 5013 0.8966 0.8599
MDA-MB-231 AZD7762
0.37
uM
LJP6
 72
hr
 1311 2430 5013 0.4848 0.3023
MDA-MB-231 AZD8055
0.37
uM
LJP6
 72
hr
 1311 1981 5013 0.3953 0.1810
MDA-MB-231 AZD8330
0.37
uM
LJP5
 72
hr
 1311 1522 5013 0.3037 0.0570
MDA-MB-231 Barasertib
0.37
uM
LJP5
 72
hr
 1311 1670 5013 0.3332 0.0970