LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Mitoxantrone
10.0
uM
LJP5
 72
hr
 1311 786 5013 0.1569 -0.1418
MDA-MB-231 Mitoxantrone
10.0
uM
LJP6
 72
hr
 1311 560 5013 0.1118 -0.2030
MDA-MB-231 MK2206
10.0
uM
LJP6
 72
hr
 1311 3977 5013 0.7934 0.7202
MDA-MB-231 Neratinib
10.0
uM
LJP5
 72
hr
 1311 2940 5013 0.5866 0.4400
MDA-MB-231 Nilotinib
10.0
uM
LJP5
 72
hr
 1311 1162 5013 0.2319 -0.0403
MDA-MB-231 Nintedanib
10.0
uM
LJP6
 72
hr
 1311 4297 5013 0.8572 0.8065
MDA-MB-231 NU7441
10.0
uM
LJP5
 72
hr
 1311 2194 5013 0.4377 0.2384
MDA-MB-231 Dactolisib
10.0
uM
LJP5
 72
hr
 1311 2172 5013 0.4333 0.2325
MDA-MB-231 NVP-TAE684
10.0
uM
LJP6
 72
hr
 1311 1051 5013 0.2097 -0.0703
MDA-MB-231 Palbociclib
10.0
uM
LJP6
 72
hr
 1311 2153 5013 0.4294 0.2273
MDA-MB-231 PD0325901
10.0
uM
LJP5
 72
hr
 1311 1263 5013 0.2519 -0.0132
MDA-MB-231 PD0325901
10.0
uM
LJP6
 72
hr
 1311 1212 5013 0.2419 -0.0268
MDA-MB-231 PD173074
10.0
uM
LJP6
 72
hr
 1311 846 5013 0.1688 -0.1257
MDA-MB-231 PD184352
10.0
uM
LJP5
 72
hr
 1311 1877 5013 0.3745 0.1529
MDA-MB-231 Pelitinib
10.0
uM
LJP5
 72
hr
 1311 1052 5013 0.2099 -0.0701
MDA-MB-231 PF431396
10.0
uM
LJP5
 72
hr
 1311 902 5013 0.1801 -0.1105
MDA-MB-231 PF477736
10.0
uM
LJP5
 72
hr
 1311 1319 5013 0.2631 0.0020
MDA-MB-231 PF562271
10.0
uM
LJP6
 72
hr
 1311 883 5013 0.1761 -0.1158
MDA-MB-231 PHA-665752
10.0
uM
LJP5
 72
hr
 1311 844 5013 0.1684 -0.1263
MDA-MB-231 PHA-793887
10.0
uM
LJP6
 72
hr
 1311 742 5013 0.1481 -0.1537
MDA-MB-231 PI103
10.0
uM
LJP6
 72
hr
 1311 1382 5013 0.2758 0.0192
MDA-MB-231 PLX-4720
10.0
uM
LJP5
 72
hr
 1311 3679 5013 0.7339 0.6396
MDA-MB-231 QL-X-138
10.0
uM
LJP6
 72
hr
 1311 940 5013 0.1876 -0.1003
MDA-MB-231 QL-XII-47
10.0
uM
LJP6
 72
hr
 1311 1087 5013 0.2169 -0.0606
MDA-MB-231 Radicicol
10.0
uM
LJP5
 72
hr
 1311 1236 5013 0.2467 -0.0203