LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Dasatinib
10.0
uM
LJP6
 72
hr
 1311 677 5013 0.1351 -0.1714
MDA-MB-231 Dovitinib
10.0
uM
LJP5
 72
hr
 1311 2027 5013 0.4044 0.1934
MDA-MB-231 Enzastaurin
10.0
uM
LJP5
 72
hr
 1311 5142 5013 1.0258 1.0349
MDA-MB-231 Erlotinib
10.0
uM
LJP5
 72
hr
 1311 3708 5013 0.7397 0.6475
MDA-MB-231 Foretinib
10.0
uM
LJP5
 72
hr
 1311 787 5013 0.1570 -0.1417
MDA-MB-231 R406
10.0
uM
LJP6
 72
hr
 1311 1817 5013 0.3624 0.1365
MDA-MB-231 Pictilisib
10.0
uM
LJP6
 72
hr
 1311 2597 5013 0.5181 0.3473
MDA-MB-231 Gefitinib
10.0
uM
LJP6
 72
hr
 1311 4569 5013 0.9114 0.8800
MDA-MB-231 Geldanamycin
10.0
uM
LJP5
 72
hr
 1311 786 5013 0.1568 -0.1420
MDA-MB-231 Geldanamycin
10.0
uM
LJP6
 72
hr
 1311 797 5013 0.1591 -0.1389
MDA-MB-231 GSK1059615
10.0
uM
LJP5
 72
hr
 1311 2194 5013 0.4377 0.2384
MDA-MB-231 GSK1059615
10.0
uM
LJP6
 72
hr
 1311 2064 5013 0.4118 0.2034
MDA-MB-231 GSK1904529A
10.0
uM
LJP6
 72
hr
 1311 4531 5013 0.9038 0.8697
MDA-MB-231 Omipalisib
10.0
uM
LJP6
 72
hr
 1311 626 5013 0.1250 -0.1851
MDA-MB-231 GSK 690693
10.0
uM
LJP5
 72
hr
 1311 4646 5013 0.9267 0.9007
MDA-MB-231 GW843682X
10.0
uM
LJP6
 72
hr
 1311 1137 5013 0.2269 -0.0471
MDA-MB-231 HG-5-113-01
10.0
uM
LJP5
 72
hr
 1311 1318 5013 0.2629 0.0017
MDA-MB-231 HG-5-88-01
10.0
uM
LJP6
 72
hr
 1311 2950 5013 0.5884 0.4426
MDA-MB-231 Imatinib
10.0
uM
LJP6
 72
hr
 1311 4460 5013 0.8897 0.8507
MDA-MB-231 JNK-9L
10.0
uM
LJP6
 72
hr
 1311 960 5013 0.1915 -0.0950
MDA-MB-231 JW-7-24-1
10.0
uM
LJP6
 72
hr
 1311 1172 5013 0.2338 -0.0377
MDA-MB-231 Lapatinib
10.0
uM
LJP6
 72
hr
 1311 3377 5013 0.6736 0.5580
MDA-MB-231 LDN-193189
10.0
uM
LJP5
 72
hr
 1311 641 5013 0.1279 -0.1811
MDA-MB-231 Linifanib
10.0
uM
LJP6
 72
hr
 1311 2666 5013 0.5318 0.3658
MDA-MB-231 Linsitinib
10.0
uM
LJP5
 72
hr
 1311 4148 5013 0.8274 0.7663